DOK1 Protein (AA 1-481, full length) (His-SUMO Tag)
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- Target See all DOK1 Proteins
- DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-481
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DOK1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MDGAVMEGPL FLQSQRFGTK RWRKTWAVLY PASPHGVARL EFFDHKGSSS GGGRGSSRRL DCKVIRLAEC VSVAPVTVET PPEPGATAFR LDTAQRSHLL AADAPSSAAW VQTLCRNAFP KGSWTLAPTD NPPKLSALEM LENSLYSPTW EGSQFWVTVQ RTEAAERCGL HGSYVLRVEA ERLTLLTVGA QSQILEPLLS WPYTLLRRYG RDKVMFSFEA GRRCPSGPGT FTFQTAQGND IFQAVETAIH RQKAQGKAGQ GHDVLRADSH EGEVAEGKLP SPPGPQELLD SPPALYAEPL DSLRIAPCPS QDSLYSDPLD STSAQAGEGV QRKKPLYWDL YEHAQQQLLK AKLTDPKEDP IYDEPEGLAP VPPQGLYDLP REPKDAWWCQ ARVKEEGYEL PYNPATDDYA VPPPRSTKPL LAPKPQGPAF PEPGTATGSG IKSHNSALYS QVQKSGASGS WDCGLSRVGT DKTGVKSEGS T
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product DOK1 Protein
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Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 1-481) protein (GST tag)
DOK1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 1-481) protein (Strep Tag)Crystallography grade DOK1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 1-482) protein (Strep Tag)Crystallography grade DOK1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 1-481), (full length) protein (His-SUMO Tag)DOK1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) protein (Myc-DYKDDDDK Tag)DOK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
- Alternative Name
- DOK1 (DOK1 Products)
- Synonyms
- P62DOK Protein, Dok-1 Protein, AW557123 Protein, p62DOK Protein, dok1 Protein, zgc:76914 Protein, docking protein 1 Protein, docking protein 1b Protein, DOK1 Protein, Dok1 Protein, dok1b Protein
- Background
- DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assbly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
- Molecular Weight
- 68.4 kDa
- UniProt
- Q99704
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