PLCD4 Protein (AA 1-762, full length) (His-SUMO Tag)
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- Target See all PLCD4 Proteins
- PLCD4 (Phospholipase C, delta 4 (PLCD4))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-762
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PLCD4 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MASLLQDQLT TDQDLLLMQE GMPMRKVRSK SWKKLRYFRL QNDGMTVWHA RQARGSAKPS FSISDVETIR NGHDSELLRS LAEELPLEQG FTIVFHGRRS NLDLMANSVE EAQIWMRGLQ LLVDLVTSMD HQERLDQWLS DWFQRGDKNQ DGKMSFQEVQ RLLHLMNVEM DQEYAFSLFQ AADTSQSGTL EGEEFVQFYK ALTKRAEVQE LFESFSADGQ KLTLLEFLDF LQEEQKERDC TSELALELID RYEPSDSGKL RHVLSMDGFL SYLCSKDGDI FNPACLPIYQ DMTQPLNHYF ICSSHNTYLV GDQLCGQSSV EGYIRALKRG CRCVEVDVWD GPSGEPVVYH GHTLTSRILF KDVVATVAQY AFQTSDYPVI LSLETHCSWE QQQTMARHLT EILGEQLLST TLDGVLPTQL PSPEELRRKI LVKGKKLTLE EDLEYEEEEA EPELEESELA LESQFETEPE PQEQNLQNKD KKKKSKPILC PALSSLVIYL KSVSFRSFTH SKEHYHFYEI SSFSETKAKR LIKEAGNEFV QHNTWQLSRV YPSGLRTDSS NYNPQELWNA GCQMVAMNMQ TAGLEMDICD GHFRQNGGCG YVLKPDFLRD IQSSFHPEKP ISPFKAQTLL IQVISGQQLP KVDKTKEGSI VDPLVKVQIF GVRLDTARQE TNYVENNGFN PYWGQTLCFR VLVPELAMLR FVVMDYDWKS RNDFIGQYTL PWTCMQQGYR HIHLLSKDGI SLRPASIFVY ICIQEGLEGD ES
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product PLCD4 Protein
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Phospholipase C, delta 4 (PLCD4) (AA 1-762) protein (GST tag)
PLCD4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Phospholipase C, delta 4 (PLCD4) (AA 18-127) protein (GST tag)PLCD4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Phospholipase C, delta 4 (PLCD4) (AA 1-762) protein (Strep Tag)Crystallography grade PLCD4 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Phospholipase C, delta 4 (PLCD4) (AA 1-807) protein (Strep Tag)Crystallography grade PLCD4 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Phospholipase C, delta 4 (PLCD4) (AA 1-762), (full length) protein (His-SUMO Tag)PLCD4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Phospholipase C, delta 4 (PLCD4) protein (Myc-DYKDDDDK Tag)PLCD4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- PLCD4 (Phospholipase C, delta 4 (PLCD4))
- Alternative Name
- PLCD4 (PLCD4 Products)
- Synonyms
- PLCD4 Protein, PLCL3 Protein, si:dkeyp-84a8.7 Protein, 4921507K24Rik Protein, phospholipase C eta 1 Protein, phospholipase C delta 4 Protein, phospholipase C, delta 4a Protein, phospholipase C, delta 4 Protein, phospholipase C delta 4 L homeolog Protein, PLCH1 Protein, PLCD4 Protein, plcd4a Protein, plcd4 Protein, Plcd4 Protein, plcd4.L Protein
- Background
- Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca2+ from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca2+ mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.
- Molecular Weight
- 103.53 kDa
- UniProt
- Q9BRC7
- Pathways
- Inositol Metabolic Process
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