WDR5 Protein (AA 2-334) (His-SUMO Tag)
-
- Target See all WDR5 Proteins
- WDR5 (WD Repeat Domain 5 (WDR5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-334
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This WDR5 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ATEEKKPETE AARAQPTPSS SATQSKPTPV KPNYALKFTL AGHTKAVSSV KFSPNGEWLA SSSADKLIKI WGAYDGKFEK TISGHKLGIS DVAWSSDSNL LVSASDDKTL KIWDVSSGKC LKTLKGHSNY VFCCNFNPQS NLIVSGSFDE SVRIWDVKTG KCLKTLPAHS DPVSAVHFNR DGSLIVSSSY DGLCRIWDTA SGQCLKTLID DDNPPVSFVK FSPNGKYILA ATLDNTLKLW DYSKGKCLKT YTGHKNEKYC IFANFSVTGG KWIVSGSEDN LVYIWNLQTK EIVQKLQGHT DVVISTACHP TENIIASAAL ENDKTIKLWK SDC
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product WDR5 Protein
-
WD Repeat Domain 5 (WDR5) (AA 1-334) protein (GST tag)
WDR5 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
WD Repeat Domain 5 (WDR5) (AA 16-120) protein (GST tag)WDR5 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
WD Repeat Domain 5 (WDR5) (AA 1-334) protein (His tag)WDR5 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
WD Repeat Domain 5 (WDR5) (AA 2-334) protein (His tag)Crystallography grade WDR5 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
WD Repeat Domain 5 (WDR5) (AA 2-334) protein (His-SUMO Tag)WDR5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
WD Repeat Domain 5 (WDR5) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)WDR5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
WD Repeat Domain 5 (WDR5) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)WDR5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Target
- WDR5 (WD Repeat Domain 5 (WDR5))
- Alternative Name
- WDR5 (WDR5 Products)
- Synonyms
- BIG-3 Protein, SWD3 Protein, 2410008O07Rik Protein, AA408785 Protein, AA960360 Protein, Big Protein, Big-3 Protein, zgc:56591 Protein, zgc:76895 Protein, wu:fk47f04 Protein, wdr5-a Protein, MGC80538 Protein, wdr5-b Protein, MGC81485 Protein, big-3 Protein, swd3 Protein, xwdr5 Protein, WDR5B Protein, WD repeat domain 5 Protein, WD repeat domain 5 L homeolog Protein, WD repeat domain 5 S homeolog Protein, WDR5 Protein, Wdr5 Protein, wdr5 Protein, wdr5.L Protein, wdr5.S Protein
- Background
- Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
- Molecular Weight
- 52.4 kDa
- UniProt
- P61964
-
