CD276 Protein (CD276) (partial) (His tag)
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- Target See all CD276 Proteins
- CD276
- Protein Type
- Recombinant
- Protein Characteristics
- partial
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD276 protein is labelled with His tag.
- Application
- Western Blotting (WB)
- Sequence
- Val 29 - Phe 244
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
- Top Product
- Discover our top product CD276 Protein
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- Application Notes
- This recombinant protein can be used for WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- Target
- CD276
- Alternative Name
- B7-H3 (CD276 Products)
- Synonyms
- sc:d0645 Protein, zgc:158279 Protein, 6030411F23Rik Protein, AU016588 Protein, B7RP-2 Protein, B7h3 Protein, B7H3 Protein, 4Ig-B7-H3 Protein, B7-H3 Protein, CD276 molecule Protein, CD276 molecule S homeolog Protein, CD276 antigen Protein, Cd276 molecule Protein, CD276 Protein, cd276.S Protein, cd276 Protein, Cd276 Protein
- Background
- B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.
- Molecular Weight
- 25.4 kDa
- Gene ID
- 102657
- NCBI Accession
- NP_598744
- UniProt
- Q8VE98
- Pathways
- Cancer Immune Checkpoints
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