IGF1 Protein (AA 49-118) (GST tag)
Quick Overview for IGF1 Protein (AA 49-118) (GST tag) (ABIN7479625)
Target
See all IGF1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 49-118
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Purification tag / Conjugate
- This IGF1 protein is labelled with GST tag.
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Sequence
- GPETLCGAEL VDALQFVCGP RGFYFNKPTG YGSSIRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPTKSA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS buffer, 20mM GSH
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Storage
- 4 °C
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- IGF1 (Insulin-Like Growth Factor 1 (IGF1))
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Alternative Name
- Insulin-like growth factor I
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Background
- Background: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.
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Molecular Weight
- 35.1 kD
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NCBI Accession
- NM_001082479
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UniProt
- P08025
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Pathways
- RTK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
Target
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