Glutaredoxin 2 Protein (GRX2) (His tag)
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- Target See all Glutaredoxin 2 (GRX2) Proteins
- Glutaredoxin 2 (GRX2)
- Protein Type
- Recombinant
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Origin
- Saccharomyces cerevisiae
- Host
- Please inquire
- Purification tag / Conjugate
- This Glutaredoxin 2 protein is labelled with His tag.
- Application
- ELISA, Western Blotting (WB)
- Characteristics
- Recombinant Yeast Glutaredoxin 2
- Purity
- > 90 % as determined by SDS-PAGE
- Top Product
- Discover our top product GRX2 Protein
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- Application Notes
- ELISA, Western Blot, strongly binds to glutathione, reduced and oxidized.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Glutaredoxin-2 solution contains 25mM Tris-HCl pH-7.5 and 0.01% Na Azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- Glutaredoxin 2 (GRX2)
- Alternative Name
- Glutaredoxin 2 (GRX2 Products)
- Synonyms
- ECK1049 Protein, JW1051 Protein, CGI-133 Protein, GRX2 Protein, 1700010P22Rik Protein, AI645710 Protein, Grx2 Protein, glutaredoxin 2 (Grx2) Protein, glutaredoxin Grx2 Protein, thioredoxin Protein, glutaredoxin 2 Protein, glutaredoxin 2 (thioltransferase) Protein, grxB Protein, grx2 Protein, AF_RS10790 Protein, GLRX2 Protein, Glrx2 Protein
- Background
- Glutaredoxin-2 Saccharamyces cerevisiae Recombinant conaining 6x His tag at C-terminus produced in E. coli is a single, non-glycosylated, Polypeptide chain having a molecular mass of 17 kDa. Introduction: GLRX2 is a multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage. Glutaredoxins are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions. Synonyms: Thioltransferase, Glutathione-dependent oxidoreductase 2, TTR, TTR1, GLRX2, GRX2, GRX-2, GLRX-2, Glutaredoxin 2.
- Pathways
- Cell RedoxHomeostasis
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