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CRNN Protein (AA 1-495) (His tag)

CRNN Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN666956
  • Target See all CRNN Proteins
    CRNN (Cornulin (CRNN))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-495
    Origin
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CRNN protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    CRNN, 1-495aa, Human, His tag, E.coli
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product CRNN Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol
    Storage
    4 °C
  • Target
    CRNN (Cornulin (CRNN))
    Alternative Name
    CRNN (CRNN Products)
    Synonyms
    C1orf10 Protein, DRC1 Protein, PDRC1 Protein, SEP53 Protein, RGD1311778 Protein, Gm1015 Protein, cornulin Protein, CRNN Protein, Crnn Protein, LOC100359146 Protein
    Background
    CRNN is a member of the 'fused gene' family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. It contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This protein, also Known as Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest. Recombinant CRNN protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DRC1, PDRC1, SEP53, Cornulin 53 kDa putative calcium binding protein, 53 kDa squamous epithelial induced stress protein, 58 kDa heat shock protein, C1orf10, Squamous epithelial heat shock protein 53, Tumor related protein. NCBI no.: AAH30807
    Molecular Weight
    55.7 kDa (515aa)
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