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Transgelin Protein (TAGLN) (AA 1-201) (His tag)

TAGLN Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS-PAGE SDS
Catalog No. ABIN667026
  • Target See all Transgelin (TAGLN) Proteins
    Transgelin (TAGLN)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-201
    Origin
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Transgelin protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    TAGLN, 1-201aa, Human, His tag, E.coli
    Purity
    > 85 % by SDS-PAGE
    Top Product
    Discover our top product TAGLN Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol 1mM DTT
    Storage
    4 °C
  • Target
    Transgelin (TAGLN)
    Alternative Name
    TAGLN (TAGLN Products)
    Synonyms
    MGC68550 Protein, sm22 Protein, smcc Protein, tagln1 Protein, ws3-10 Protein, MGC107855 Protein, SM22 Protein, SMCC Protein, TAGLN1 Protein, WS3-10 Protein, Sm22 Protein, Sm22a Protein, Ws310 Protein, SM22A Protein, zgc:153186 Protein, transgelin L homeolog Protein, transgelin Protein, tagln.L Protein, tagln Protein, LOC732906 Protein, TAGLN Protein, tagl Protein, LOC100009332 Protein, Tagln Protein
    Background
    TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein that belongs to the calponin family. This protein is expressed abundantly in fibroblasts and smooth muscle. It is involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence. During embryogenesis, TAGLN is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. It is downregulated in several transformed cell lines, indicating that a reduction of TAGLN expression may be an early indicator of the onset of transformation. Recombinant human TAGLN protein, fused to his-tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: SM22, SMCC, TAGLN1, WS3-10, Transgelin, SM 22, SM22 alpha, SMCC, Smooth muscle protein 22-alpha, WS3 10. NCBI no.: NP_001001522
    Molecular Weight
    24.8 kDa (221aa) confirmed by MALDI-TOF
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