DIRAS1 Protein (AA 1-195) (His tag)
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- Target See all DIRAS1 Proteins
- DIRAS1 (DIRAS Family, GTP-Binding RAS-Like 1 (DIRAS1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-195
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DIRAS1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- DIRAS1, 1-195aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS – PAGE
- Top Product
- Discover our top product DIRAS1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol, 1mM DTT, 0.1M NaCl, 1mM EDTA.
- Storage
- 4 °C
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- Target
- DIRAS1 (DIRAS Family, GTP-Binding RAS-Like 1 (DIRAS1))
- Alternative Name
- DIRAS1 (DIRAS1 Products)
- Synonyms
- Di-Ras1 Protein, GBTS1 Protein, RIG Protein, Gbts1 Protein, diras1 Protein, fi18d11 Protein, wu:fi18d11 Protein, zgc:55360 Protein, si:dkey-97k23.2 Protein, rig Protein, gbts1 Protein, di-ras1 Protein, MGC146486 Protein, DIRAS family GTPase 1 Protein, DIRAS family, GTP-binding RAS-like 1 Protein, DIRAS family, GTP-binding RAS-like 1a Protein, DIRAS family, GTP-binding RAS-like 1b Protein, DIRAS family GTP binding RAS like 1 Protein, DIRAS1 Protein, Diras1 Protein, diras1a Protein, diras1b Protein, diras1 Protein
- Background
- DIRAS1 belongs to a distinct branch of the functionally diverse Ras superfamily of monomeric GTPases. Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis. DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. Recombinant human DIRAS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Di-Ras1, FLJ42681, GBTS1, RIG, GTP-binding protein Di-Ras1. NCBI no.: NP_660156
- Molecular Weight
- 24.1 kDa (215aa), confirmed by MALDI-TOF
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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