CDA Protein (AA 1-146) (His tag)
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- Target See all CDA Proteins
- CDA (Cytidine Deaminase (CDA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-146
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CDA protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- CDA, 1-146aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CDA Protein
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Cytidine Deaminase (CDA) (AA 1-146) protein (His tag)
CDA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Cytidine Deaminase (CDA) (AA 1-146) protein (GST tag)CDA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Cytidine Deaminase (CDA) (AA 1-146) protein (Strep Tag)Crystallography grade CDA Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Cytidine Deaminase (CDA) (AA 1-146) protein (Strep Tag)Crystallography grade CDA Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Cytidine Deaminase (CDA) (AA 1-146), (full length) protein (GST tag)CDA Origin: Human Host: Escherichia coli (E. coli) Recombinant 95 % ELISA, SDS, WB
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 1 mM DTT, 2 mM EDTA, 100 mM NaCl, 40% Glycerol
- Storage
- 4 °C
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- Target
- CDA (Cytidine Deaminase (CDA))
- Alternative Name
- CDA (CDA Products)
- Synonyms
- CDA Protein, cda Protein, zgc:77948 Protein, DDBDRAFT_0188181 Protein, DDBDRAFT_0230205 Protein, DDB_0188181 Protein, DDB_0230205 Protein, CDD Protein, 2210401N16Rik Protein, cytidine deaminase Protein, cytidine aminohydrolase; CDA Protein, cytidine deaminase b Protein, Cytidine deaminase Protein, cytidine deaminase Cdd Protein, CDA Protein, cda Protein, VNG_RS03500 Protein, OE_RS03485 Protein, CDD1 Protein, cdd Protein, cdab Protein, cdd-1 Protein, cdd-2 Protein, CNC04940 Protein, Tb09.160.1680 Protein, Cda Protein
- Background
- CDA (Cytidine deaminase) is an enzyme that scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. The protein also catalyzes the deamination of chemotherapeutic cytosine nucleoside analogs such as Ara-C and 5-azacytidine, which results in the loss of their cytotoxic and antitumor function. It can form homotetramers and is mainly expressed in granulocytes. Recombinant human CDA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: CDD, Cytidine aminohydrolase, Cytosine nucleoside deaminase, Cytidine deaminase. NCBI no.: AAH54036
- Molecular Weight
- 18.3 kDa(166aa), confirmed by MALDI-TOF
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