ATF3 Protein (AA 1-181)
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- Target See all ATF3 Proteins
- ATF3 (Activating Transcription Factor 3 (ATF3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-181
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Characteristics
- ATF3, 1-181aa, Human, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ATF3 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl, pH8.0, 2M Urea, 20%Glycerol
- Storage
- 4 °C
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- Target
- ATF3 (Activating Transcription Factor 3 (ATF3))
- Alternative Name
- ATF3 (ATF3 Products)
- Synonyms
- zgc:55526 Protein, ATF3 Protein, LRG-21 Protein, LRF-1 Protein, LRFI Protein, atf-3 Protein, activating transcription factor 3 Protein, activating transcription factor 3 L homeolog Protein, atf3 Protein, ATF3 Protein, Atf3 Protein, atf3.L Protein
- Background
- ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter. Synonyms: Activating transcription factor 3, ATF3deltaZip2, ATF3deltaZip2c, ATF3deltaZip3, cAMP dependent transcription factor ATF3, Cyclic AMP dependent transcription factor ATF3, Cyclic AMP-dependent transcription factor ATF-3. NCBI no.: NP_001665
- Molecular Weight
- 20.6kDa (181aa)
- Pathways
- Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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