RGS17 Protein (AA 1-210) (His tag)
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- Target See all RGS17 Proteins
- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-210
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RGS17 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- RGS17, 1-210aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
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Regulator of G-Protein Signaling 17 (RGS17) (AA 1-210) protein (GST tag)
RGS17 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Regulator of G-Protein Signaling 17 (RGS17) (AA 111-210) protein (GST tag)RGS17 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Regulator of G-Protein Signaling 17 (RGS17) (AA 1-210) protein (Strep Tag)Crystallography grade RGS17 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Regulator of G-Protein Signaling 17 (RGS17) (AA 1-210) protein (Strep Tag)Crystallography grade RGS17 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Regulator of G-Protein Signaling 17 (RGS17) protein (His tag)RGS17 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl,1mM DTT
- Storage
- 4 °C
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- Target
- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
- Alternative Name
- RGS17 (RGS17 Products)
- Synonyms
- RGS17 Protein, zgc:92802 Protein, MGC179306 Protein, RGS-17 Protein, RGSZ2 Protein, hRGS17 Protein, 6430507P11Rik Protein, Rgsz2 Protein, regulator of G protein signaling 17 Protein, regulator of G-protein signaling 17 Protein, RGS17 Protein, Rgs17 Protein, rgs17 Protein
- Background
- RGS17, also known as regulator of G-protein signaling 17, attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. It plays an important role in termination of signalling by mu opioid receptors and development of tolerance to opioid analgesic drugs. Recombinant human RGS17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Regulator of G-protein signaling 17, hRGS17, RGS-17, RGSZ2. NCBI no.: NP_036551
- Molecular Weight
- 26.5 kDa(230aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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