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HDDC3 Protein (AA 1-140) (His tag)

HDDC3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667594
  • Target See all HDDC3 Proteins
    HDDC3 (HD Domain Containing 3 (HDDC3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-140
    Origin
    • 5
    • 1
    Human
    Source
    • 4
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HDDC3 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    HDDC3, 1-140aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product HDDC3 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT
    Storage
    4 °C
  • Target
    HDDC3 (HD Domain Containing 3 (HDDC3))
    Alternative Name
    HDDC3 (HDDC3 Products)
    Synonyms
    MESH1 Protein, zgc:110184 Protein, 1110033O09Rik Protein, C86475 Protein, RGD1311839 Protein, HD domain containing 3 Protein, HD domain containing 3 S homeolog Protein, hddc3 Protein, HDDC3 Protein, hddc3.S Protein, Hddc3 Protein
    Background
    HDDC3, also known as guanosine-3',5'-bis(diphosphate)-pyrophosphohydrolase MESH1, contains an active site for ppGpp hydrolysis and a conserved His-Asp-box motif for Mn(2+) binding. Consistent with these structural data, HDDC3 efficiently catalyzes hydrolysis of guanosine 3',5'-diphosphate (ppGpp) both in vitro and in vivo. HDDC3 also suppresses SpoT-deficient lethality and RelA-induced delayed cell growth in bacteria. Recombinant human HDDC3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Guanosine-3',5'-bis(diphosphate)-pyrophosphohydrolase MESH1, MESH1, ppGpp. NCBI no.: NP_940929
    Molecular Weight
    17.9 kDa (160aa), confirmed by MALDI-TOF
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