RAB23 Protein (AA 1-234) (His tag)

Catalog No. ABIN667606

Product Details

Target: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Protein Type: Recombinant

Protein Characteristics: AA 1-234

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This RAB23 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: RAB23, 1-234aa, Human, His tag E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 1mM DTT, 0.1mM PMSF

Storage: 4 °C

Target Details

Target: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Alternative Name: RAB23 (RAB23 Products)

Synonyms: MGC82152 Protein, hspc137 Protein, zgc:110261 Protein, AW545388 Protein, opb Protein, opb2 Protein, HSPC137 Protein, Rab23-like Protein, RAB23, member RAS oncogene family S homeolog Protein, RAB23, member RAS oncogene family Protein, ras-related protein Rab-23 Protein, rab23.S Protein, RAB23 Protein, rab23 Protein, Rab23 Protein

Background: RAB23, also known as ras-related protein Rab23, is a member of the Rab family of proteins and localizes to the cytoplasmic side of the cell membrane. This protein is thought to to play a role in intracellular protein transportation and signal transduction mediated by small GTPases. RAB23 is an essential negative regulator of the Sonic hedgehog signaling pathway. Mutations in the gene encoding RAB23 may result in Carpenter syndrome a condition characterized by obesity, cardiac defects, polysyndactyly and craniosynostosis. Recombinant human RAB23 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Ras-related protein Rab-23, DKFZp781H0695, HSPC137, MGC8900. NCBI no.: NP_057361

Molecular Weight: 28.5 kDa (254aa), confirmed by MALDI-TOF

Pathways: Tube Formation