GIPC1 Protein (AA 1-333) (His tag)

Catalog No. ABIN667795

Product Details

Target: GIPC1 (GIPC PDZ Domain Containing Family, Member 1 (GIPC1))

Protein Type: Recombinant

Protein Characteristics: AA 1-333

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This GIPC1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: GIPC1, 1-333aa, Human, His tag, E.coli

Purity: > 95 % by SDS-PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol 1mM DTT, 0.1M NaCl, and 1mM EDTA

Storage: 4 °C

Target Details

Target: GIPC1 (GIPC PDZ Domain Containing Family, Member 1 (GIPC1))

Alternative Name: GIPC1 (GIPC1 Products)

Synonyms: C19orf3 Protein, GIPC Protein, GLUT1CBP Protein, Hs.6454 Protein, IIP-1 Protein, NIP Protein, RGS19IP1 Protein, SEMCAP Protein, SYNECTIIN Protein, SYNECTIN Protein, TIP-2 Protein, XGIPC Protein, kermit Protein, rgs19ip1 Protein, gipc3 Protein, iip-1 Protein, Kermit Protein, semcap Protein, glut1cbp Protein, synectiin Protein, GIPC1 Protein, Glut1CIP Protein, Rgs19ip1 Protein, Semcap1 Protein, TaxIP2 Protein, Gipc Protein, Rgs19 Protein, GIPC PDZ domain containing family member 1 Protein, GIPC PDZ domain containing family member 1 L homeolog Protein, GIPC PDZ domain containing family, member 1 Protein, RGS-GAIP interacting protein GIPC Protein, PDZ domain-containing protein GIPC3 Protein, putative rgs-gaip interacting protein gipc Protein, GIPC1 Protein, gipc1.L Protein, gipc1 Protein, Gipc1 Protein, LOC692815 Protein, LOC5576629 Protein, Smp_170870 Protein

Background: GIPC1 is a PDZ domain containing protein that interacts with RGS-GAIP and the viral oncoprotein TAX, which transactivates viral and cellular promoters through interactions with various transcription factors. GIPC specifically localizes to clusters of vesicles near the plasma membrane and participates in G protein-coupled signaling pathway involved in regulating Clathrin-coated vesicular trafficking. GIPC also associates with membrane bound Semaphorin F (M-SemF), which is involved in neuronal axon growth, and it appears to regulate the subcellular distribution of M-SemF in the brain. Recombinant human GIPC1 protein, fused to at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: C19orf3, GIPC, GLUT1CBP, Hs.6454, IIP-1, NIP, SEMCAP, SYNECTIIN, SYNECTIN, TIP-2, RGS19IP1, PDZ domain-containing protein GIPC1, Chromosome 19 open reading frame 3, GIPC, IIP 1, TIP 2, GIPC 1. NCBI no.: NP_974199

Molecular Weight: 38.2 kDa (353aa) confirmed by MALDI-TOF

Pathways: Dicarboxylic Acid Transport