PYCR1 Protein (AA 1-319) (His tag)
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- Target See all PYCR1 Proteins
- PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-319
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PYCR1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PYCR1, 1-319aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product PYCR1 Protein
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Pyrroline-5-Carboxylate Reductase 1 (PYCR1) (AA 1-319) protein (His tag)
PYCR1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Pyrroline-5-Carboxylate Reductase 1 (PYCR1) (AA 1-319) protein (GST tag)PYCR1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Pyrroline-5-Carboxylate Reductase 1 (PYCR1) (AA 2-319) protein (His tag)Crystallography grade PYCR1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Pyrroline-5-Carboxylate Reductase 1 (PYCR1) (AA 2-309) protein (His tag)Crystallography grade PYCR1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Pyrroline-5-Carboxylate Reductase 1 (PYCR1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PYCR1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Pyrroline-5-Carboxylate Reductase 1 (PYCR1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PYCR1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.5) containing 10% Glycerol
- Storage
- 4 °C
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- Target
- PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))
- Alternative Name
- PYCR1 (PYCR1 Products)
- Synonyms
- arcl2b Protein, p5c Protein, p5cr Protein, pig45 Protein, pp222 Protein, pro3 Protein, pycr Protein, ARCL2B Protein, ARCL3B Protein, P5C Protein, P5CR Protein, PIG45 Protein, PP222 Protein, PRO3 Protein, PYCR Protein, zgc:73112 Protein, pyrroline-5-carboxylate reductase family, member 1 L homeolog Protein, pyrroline-5-carboxylate reductase 1 Protein, pyrroline-5-carboxylate reductase 1a Protein, pycr1.L Protein, PYCR1 Protein, Pycr1 Protein, pycr1a Protein
- Background
- PYCR1 is a universal housekeeping enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. It forms a homopolymer and localizes to the mitochondrion. Defects in PYCR1 are the cause of cutis laxa autosomal recessive type 2B (ARCL2B). Recombinant human PYCR1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Pyrroline-5-carboxylate reductase 1, ARCL2B, P5C, P5CR, PIG45, PP222, PRO3. NCBI no.: NP_008838
- Molecular Weight
- 35.5 kDa(339aa), confirmed by MALDI-TOF
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