Lipocalin 2 Protein (LCN2) (AA 21-198) (His tag)
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- Target See all Lipocalin 2 (LCN2) Proteins
- Lipocalin 2 (LCN2)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-198
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Lipocalin 2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- LCN2, 21-198aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product LCN2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT, 50mM NaCl
- Storage
- 4 °C
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- Target
- Lipocalin 2 (LCN2)
- Alternative Name
- LCN2 (LCN2 Products)
- Synonyms
- LCN2 Protein, 24p3 Protein, MSFI Protein, NGAL Protein, AW212229 Protein, Sip24 Protein, lipocalin 2 Protein, LCN2 Protein, Lcn2 Protein
- Background
- Neutrophil gelatinase-associated lipocalin (NGAL), also known as LCN2, belongs to the calycin superfamily and Lipocalin family. LCN2 is an iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. The binding of LCN2 to bacterial siderophores is important in the innate immune response to bacterial infection. Also LCN2 functions as a growth factor. LCN2 is strongly upregulated during inflammation and is upregulated by interleukin 1 (but not TNF alpha) in humans. Recombinant human LCN2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Neutrophil gelatinase-associated lipocalin, Lipocalin-2, MSFI, NGAL, Oncogene 24p3, p25, HNL. NCBI no.: NP_005555
- Molecular Weight
- 22.8kDa (199aa), confirmed by MALDI-TOF
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis
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