DEFB4A Protein
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- Target See all DEFB4A (DEFB4) Proteins
- DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM
- Purity
- > 97 % by SDS-PAGE and HPLC analyses.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 1EU/µg of rRtSDF-1beta/CXCL12 as determined by LAL method.
- Top Product
- Discover our top product DEFB4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20° C. Further dilutions should be made in appropriate buffered solutions.
- Storage
- 4 °C/-20 °C
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- Target
- DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))
- Alternative Name
- BD-2 (DEFB4 Products)
- Synonyms
- BD-2 Protein, DEFB-2 Protein, DEFB102 Protein, DEFB2 Protein, DEFB4 Protein, HBD-2 Protein, SAP1 Protein, BD2 Protein, DEFB4P Protein, THP2 Protein, defensin beta 4A Protein, defensin beta 2 Protein, defensin beta 1 Protein, avian beta-defensin 4 Protein, defensin, beta 4A Protein, beta-defensin 2 Protein, defensin beta 4 Protein, beta defensin 2 Protein, DEFB4A Protein, Defb2 Protein, DEFB1 Protein, AvBD4 Protein, THP2 Protein, defb4 Protein, SBD2 Protein
- Background
- SDF-1alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor.
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