Translin Protein (TSN) (AA 1-228)
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- Target See all Translin (TSN) Proteins
- Translin (TSN)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-228
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MSVSEIFVEL QGFLAAEQDI REEIRKVVQS LEQTAREILT LLQGVHQGAG FQDIPKRCLK AREHFGTVKT HLTSLKTKFP AEQYYRFHEH WRFVLQRLVF LAAFVVYLET ETLVTREAVT EILGIEPDRE KGFHLDVEDY LSGVLILASE LSRLSVNSVT AGDYSRPLHI STFINELDSG FRLLNLKNDS LRKRYDGLKY DVKKVEEVVY DLSIRGFNKE TAAACVEK
- Characteristics
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Purified recombinant Human TSN protein
Expression System: E.coli - Purity
- > 90 % pure
- Top Product
- Discover our top product TSN Protein
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Translin (TSN) (AA 1-228) protein (His tag)
TSN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Translin (TSN) (AA 1-228) protein (GST tag)TSN Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Translin (TSN) (AA 115-197) protein (GST tag)TSN Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Translin (TSN) (AA 1-228) protein (Strep Tag)Crystallography grade TSN Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
- TSN protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0 mM DTT, 10 % glycerol and 100 mM NaCl.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
- Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Target
- Translin (TSN)
- Alternative Name
- TSN (TSN Products)
- Synonyms
- tsn Protein, MGC52533 Protein, TSN Protein, CG11761 Protein, Dmel\\CG11761 Protein, TB-RBP Protein, BCLF-1 Protein, C3PO Protein, RCHF1 Protein, REHF-1 Protein, TBRBP Protein, TRSLN Protein, 2610034C24Rik Protein, AU040286 Protein, translin L homeolog Protein, translin Protein, haloacid dehalogenase Protein, Translin Protein, tsn.L Protein, TSN Protein, trsn Protein, MMAH_RS03470 Protein, TAGG_RS05275 Protein, Igag_0962 Protein, MFER_RS03645 Protein, DESMU_RS01315 Protein, ARCVE_RS05265 Protein, MZHIL_RS01310 Protein, Tsn Protein
- Background
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Translin, also known as TSN, is a DNA and RNA binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin forms a ring-shaped structure, which is responsible for DNA binding, and also contains a leucine zipper motif, which is thought to enable translin to form dimers. Translin exports specific mRNAs out of the nucleus, supported by its localization in both the nuclei and cytoplasm of neurons, and regulates their translation. Recombinant human Translin protein, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: BCLF-1 protein, REHF-1 protein, RCHF1 protein, Translin protein, TBRBP protein, TRSLN - Molecular Weight
- 26.1 kDa (228 AA)
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