BCMA Protein
Quick Overview for BCMA Protein (ABIN935227)
Target
See all BCMA (TNFRSF17) ProteinsProtein Type
Origin
Source
Purity
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Sequence
- AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
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Characteristics
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Purified recombinant Human BCMA protein
Expression System: E.coli -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
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Alternative Name
- BCMA
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Background
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BCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines and plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid extracellular domain.
Alternative Names: TNFRSF17 protein, BCM protein, B-Cell Maturation Antigen protein -
Molecular Weight
- 5.3 kDa
Target
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