BCMA Protein (AA 1-54) (Fc Tag)
Quick Overview for BCMA Protein (AA 1-54) (Fc Tag) (ABIN2180644)
Target
See all BCMA (TNFRSF17) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 1-54
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Purification tag / Conjugate
- This BCMA protein is labelled with Fc Tag.
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Sequence
- AA 1-54
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Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32 kDa. As a result of glycosylation, the protein migrates as 35-40 kDa under reducing (R) condition, and 66 kDa under non-reducing (NR) condition (SDS-PAGE).
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 0.1 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
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Alternative Name
- BCMA
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Background
- Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
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Molecular Weight
- 32.0 kDa
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NCBI Accession
- NP_001183
Target
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