BCMA Protein (AA 1-54) (mFc Tag)
Quick Overview for BCMA Protein (AA 1-54) (mFc Tag) (ABIN6961108)
Target
See all BCMA (TNFRSF17) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-54
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Purification tag / Conjugate
- This BCMA protein is labelled with mFc Tag.
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Purpose
- Recombinant human BCMA protein with C-terminal mouse Fc tag
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Specificity
- BCMA(Met1-Ala54) mFc(Pro99-Lys330)
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Biological Activity Comment
- EC50=3.163
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Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) (Active) protein (hFc Tag)
TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) protein (His-Avi Tag)TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-53) (Active) protein (hFc Tag)TNFRSF17 Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54), (Trimer) (Active) protein (His-Avi Tag)TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-49) (Active) protein (His-Avi Tag)TNFRSF17 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) (Active) protein (Biotin,His-Avi Tag)TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-49) (Active) protein (Biotin,His-Avi Tag)TNFRSF17 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) (Active) protein (Fc Tag)TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54), (Trimer) (Active) protein (Biotin,His-Avi Tag)TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-184) protein (His tag)custom-made TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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Comment
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please see Certificate of Analysis for specific instructions of reconstitution.
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
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Alternative Name
- BCMA
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Background
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TNFRSF17,CD269,BCM,BCMA
B-cell maturation protein (BCMA or BCM), is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK. -
Molecular Weight
- predicted molecular mass of 32.1 kDa after removal of the signal peptide.
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Gene ID
- 608
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UniProt
- Q02223
Target
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