Collagen IV Protein
COL4
Origin: Human
Host: Human
Native
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- Target See all Collagen IV (COL4) Proteins
- Collagen IV (COL4) (Collagen, Type IV (COL4))
- Protein Type
- Native
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Origin
- Human
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Source
- Human
- Characteristics
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Purified native Human Collagen Type IV protein
Protein Source: Human placenta - Purification
- Affinity chromatography
- Sterility
- Sterile filtered
- Top Product
- Discover our top product COL4 Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Sterile filtered liquid in 0.5 M CH3COOH, with 0.01 % NaN3.
- Preservative
- Sodium azide
- Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Handling Advice
- Dilute only prior to immediate use.
- Storage
- 4 °C
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- Target
- Collagen IV (COL4) (Collagen, Type IV (COL4))
- Alternative Name
- Collagen Type IV (COL4 Products)
- Synonyms
- collagen, type IV Protein, Let-2 Protein
- Background
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Collagen IV is a major constituent of the basement membranes along with laminins, proteoglycans and enactins. It is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. It can form insoluble fibers with high tensile strength. Collagen IV is useful in detecting the loss of parts of basement membranes in carcinomas.
Description: Human placenta.
Alternative Names: Canstatin protein, Arresten protein, Collagen Of Basement Membrane alpha 1 Chain protein
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