IGFBPI Protein
-
- Target See all IGFBPI Proteins
- IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Sequence
- MAPWQCAPCS AEKLALCPPV SASCSEVTRS AGCGCCPMCA LPLGAACGVA TARCARGLSC RALPGEQQPL HALTRGQGAC VQESDASAPH AAEAGSPESP ESTEITEEEL LDNFHLMAPS EEDHSILWDA ISTYDGSKAL HVTNIKKWKE PCRIELYRVV ESLAKAQETS GEEISKFYLP NCNKNGFYHS RQCETSMDGE AGLCWCVYPW NGKRIPGSPE IRGDPNCQIY FNVQN
- Characteristics
-
Purified recombinant Human IGF BP1 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by its ability to inhibit IGF-I induced proliferation of MCF-7 is ? 0.5 µg/mL in the presence of 6 ng/mL of human IGF-I. - Purity
- > 97 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product IGFBPI Protein
-
Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 26-259) protein (His tag)
IGFBPI Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 1-259) protein (GST tag)IGFBPI Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 160-259) protein (GST tag)IGFBPI Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 26-259) protein (His tag)Crystallography grade IGFBPI Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 26-272) protein (His tag)Crystallography grade IGFBPI Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
-
- Target
- IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))
- Alternative Name
- IGF BP1 (IGFBPI Products)
- Synonyms
- cb656 Protein, igfbp1 Protein, IGFBP-1 Protein, MGC68538 Protein, afbp Protein, ibp1 Protein, pp12 Protein, igf-bp25 Protein, higfbp-1 Protein, IGFBP1 Protein, LOC100223208 Protein, LOC100305121 Protein, AFBP Protein, IBP1 Protein, IGF-BP25 Protein, PP12 Protein, hIGFBP-1 Protein, IGFBA Protein, insulin like growth factor binding protein 1 Protein, insulin-like growth factor binding protein 1a Protein, insulin like growth factor binding protein 1 S homeolog Protein, insulin like growth factor binding protein 1 L homeolog Protein, insulin-like growth factor binding protein 1 Protein, IGFBP1 Protein, igfbp1a Protein, igfbp1.S Protein, igfbp1.L Protein, igfbp1 Protein, LOC100305121 Protein, Igfbp1 Protein
- Background
-
IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, deciduas, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds to both IGF-I and IGF-II with equal affinity.
Alternative Names: IGF BP-1, IGF BP-1 protein, IGF BP 1 protein, PP12 protein, IGF BP 1, IBP-1 protein, IGF BP1, Insulin-like Growth Factor-Binding Protein 1 protein, IGF BP-1 protein, Placenta Protein 12 protein - Molecular Weight
- 25.4 kDa
- Pathways
- Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Growth Factor Binding
-
