SLC22A1 antibody
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- Target See all SLC22A1 Antibodies
- SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SLC22A1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human SLC22A1 expressed in E. coli.
- Clone
- 2C5
- Isotype
- IgG1
- Top Product
- Discover our top product SLC22A1 Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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OCT1 (SLC22A1) R61C polymorphism and response to imatinib treatment in chronic myeloid leukemia patients." in: Leukemia & lymphoma, Vol. 49, Issue 11, pp. 2222-3, (2008) (PubMed).
: "Constitutive overexpression of P-glycoprotein, rather than breast cancer resistance protein or organic cation transporter 1, contributes to acquisition of imatinib-resistance in K562 cells." in: Pharmaceutical research, Vol. 25, Issue 4, pp. 827-35, (2008) (PubMed).
: "Effective dasatinib uptake may occur without human organic cation transporter 1 (hOCT1): implications for the treatment of imatinib-resistant chronic myeloid leukemia." in: Blood, Vol. 112, Issue 8, pp. 3348-54, (2008) (PubMed).
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OCT1 (SLC22A1) R61C polymorphism and response to imatinib treatment in chronic myeloid leukemia patients." in: Leukemia & lymphoma, Vol. 49, Issue 11, pp. 2222-3, (2008) (PubMed).
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- Target
- SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
- Alternative Name
- SLC22A1 (SLC22A1 Products)
- Synonyms
- SLC22A1 antibody, OCT1 antibody, HOCT1 antibody, oct1_cds antibody, Lx1 antibody, Oct1 antibody, Orct antibody, Orct1 antibody, Roct1 antibody, SLC22A2 antibody, solute carrier family 22 member 1 antibody, solute carrier family 22 (organic cation transporter), member 1 antibody, solute carrier family 22 member 2-like antibody, SLC22A1 antibody, Slc22a1 antibody, LOC421584 antibody
- Background
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Description: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Tissue specificity: Widely expressed with high level in liver.
Aliases: OCT1, HOCT1, oct1_cds, SLC22A1
- Molecular Weight
- 61.2 kDa
- Gene ID
- 6580
- HGNC
- 6580
- Pathways
- Hormone Transport
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