GluA 3 (AA 860-871) antibody

Catalog No. ABIN1742380

Product Details

Target: GluA 3

Binding Specificity: AA 860-871

Reactivity: Cow, Human, Mouse, Pig, Rat

Host: Rabbit

Clonality: Polyclonal

Application: Immunoprecipitation (IP), Western Blotting (WB)

Specificity: Specific for GluA 3.

Purification: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Synthetic peptide of mouse GluA 3 (aa 860-871) coupled to KHL via an N-terminal cystein.

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
ICC: not tested yet
IHC: not tested yet

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handling Advice: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Storage: -20 °C

Storage Comment: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

References

Sultana, Nakaya, Dong, Abu-Asab, Qian, Tomarev: "Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice." in: Experimental neurology, Vol. 261, pp. 802-11, (2014) (PubMed).

Schmeisser, Ey, Wegener, Bockmann, Stempel, Kuebler, Janssen, Udvardi, Shiban, Spilker, Balschun, Skryabin, Dieck, Smalla, Montag, Leblond, Faure, Torquet, Le Sourd, Toro, Grabrucker, Shoichet et al.: "Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. ..." in: Nature, Vol. 486, Issue 7402, pp. 256-60, (2012) (PubMed).

Target Details

Target: GluA 3

Background: Synonyms: AMPA 3, GluR 3