A2BP1 antibody (N-Term)

Catalog No. ABIN2779139

Product Details anti-A2BP1 Antibody

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This A2BP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EYTGQTTVPD HTLNLYPPTQ THSEQSADTS AQTVSGTATQ TDDAAPTDGQ

Predicted Reactivity: Cow: 79%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Rbfox1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Rbfox1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 396 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-A2BP1 antibody (ABIN2779139)

Fogel, Wexler, Wahnich, Friedrich, Vijayendran, Gao, Parikshak, Konopka, Geschwind: "RBFOX1 regulates both splicing and transcriptional networks in human neuronal development." in: Human molecular genetics, Vol. 21, Issue 19, pp. 4171-86, (2012) (PubMed).

Target Details for A2BP1

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Alternative Name: Rbfox1 (A2BP1 Products)

Synonyms: A2BP1 antibody, fox1 antibody, a2bp1 antibody, zgc:103635 antibody, 2BP1 antibody, FOX-1 antibody, FOX1 antibody, HRNBP1 antibody, A2bp antibody, A2bp1 antibody, Hrnbp1 antibody, fox-1 antibody, RNA binding protein, fox-1 homolog 1 antibody, RNA binding fox-1 homolog 1 antibody, multicopper ferroxidase antibody, RNA binding protein, fox-1 homolog (C. elegans) 1 antibody, RBFOX1 antibody, rbfox1 antibody, FOX1 antibody, Rbfox1 antibody

Background: Rbfox1 is a RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. It prevents binding of U2AF2 to the 3'-splice site and regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.
Alias Symbols: A2bp, Hrnbp1, fox-1
Protein Size: 396

Molecular Weight: 43 kDa

Gene ID: 268859

NCBI Accession: NM_021477, NP_067452

UniProt: Q9JJ43