Gastrointestinal Tumor Associated Marker 2 (GTAM2) antibody

Catalog No. ABIN966183

Product Details

Target: Gastrointestinal Tumor Associated Marker 2 (GTAM2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Specificity: These Gastrointestinal Tumor Associated Markers are new monoclonal antibodies developed in our Monoclonal Labs against tumor cell lines

Purification: Concentrated.

Immunogen: Gastrointestinal tumor membrane fraction.

Clone: B43-2

Isotype: IgG1 kappa

Application Details

Application Notes: Immunohistochemistry: 1:50-100
Immunoblotting: 1:200-1:500.
Staining Procedure: This antibody can be used on formalin-fixed, paraffin-embedded tissue sections. Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50-1:100 in IHC. It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory.

Comment:

Recommended Positive Control: Gastric, Colon, pancreatic and Breast Carcinomas

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/ml.

Buffer: 20 mM tris-borate, 150 mM Sodium Chloride, dialyzed media RPMI 1640/D-MEM containing fetal bovine serum, BMC-6 carrier polysaccharides, carrier protein, pH 7.5

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References

Siddiki, Ho, Huang, Byrd, Lau, Yuan, Kim: "Monoclonal antibody directed against colon cancer mucin has high specificity for malignancy." in: International journal of cancer. Journal international du cancer, Vol. 54, Issue 3, pp. 467-74, (1993) (PubMed).

Osako, Yonezawa, Siddiki, Huang, Ho, Kim, Sato: "Immunohistochemical study of mucin carbohydrates and core proteins in human pancreatic tumors." in: Cancer, Vol. 71, Issue 7, pp. 2191-9, (1993) (PubMed).

Meyer, Neurand, Bartels: "[The "protective acid coat" of the skin of our domestic animals]." in: DTW. Deutsche tierärztliche Wochenschrift, Vol. 98, Issue 5, pp. 167-70, (1991) (PubMed).

Ho, Bi, Yan, Yuan, Norton, Kim: "Characterization of new pancreatic cancer-reactive monoclonal antibodies directed against purified mucin." in: Cancer research, Vol. 51, Issue 1, pp. 372-80, (1991) (PubMed).

Byrd, Ho, Lamport, Ho, Siddiki, Huang, Yan, Kim: "Relationship of pancreatic cancer apomucin to mammary and intestinal apomucins." in: Cancer research, Vol. 51, Issue 3, pp. 1026-33, (1991) (PubMed).

Hilkens, Buijs, Hilgers, Hageman, Calafat, Sonnenberg, van der Valk: "Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors." in: International journal of cancer. Journal international du cancer, Vol. 34, Issue 2, pp. 197-206, (1984) (PubMed).

Target Details

Target: Gastrointestinal Tumor Associated Marker 2 (GTAM2)