Browse our Spectrin alpha 1, Erythrocytic (SPTA1) ELISA Kits

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Spectrin alpha 1, Erythrocytic ELISA Kits (SPTA1)
On are 3 Spectrin alpha 1, Erythrocytic (SPTA1) ELISA Kits from 2 different suppliers available. Additionally we are shipping Spectrin alpha 1, Erythrocytic Antibodies (11) and many more products for this protein. A total of 15 Spectrin alpha 1, Erythrocytic products are currently listed.
AF093576, AI451697, EL2, ha, HPP, HS3, ihj, nmf4, sph, SPH3, Spna-1, Spna1, SPTA
list all ELISA KIts Gene Name GeneID UniProt
Rat SPTA1 SPTA1 289257  
SPTA1 20739 P08032
SPTA1 6708 P02549

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Mouse (Murine) Spectrin alpha 1, Erythrocytic (SPTA1) interaction partners

  1. This study demonstrates that the FGF19 (show FGF19 ELISA Kits)-SHP (show LAMC1 ELISA Kits)-LSD1 (show KDM1A ELISA Kits) axis maintains homeostasis by suppressing unnecessary autophagic breakdown of cellular components, including lipids, under nutrient-rich postprandial conditions.

  2. a new function for spectrins in the stability of invadosomes and the coupling between actin regulation and ECM (show MMRN1 ELISA Kits) degradation

  3. Calcium plays a role in regulating the expression and function of beta-adducin to sustain normal organization of the spectrin-based cytoskeleton and the differentiation properties in keratinocytes through the calmodulin/EGFR/cadherin signaling pathway.

  4. organization of a spectrin-like cytoskeleton is associated with keratinocyte differentiation, and cytoskeleton disruption is mediated by either PKCdelta (show PKCd ELISA Kits)(Thr505) phosphorylation associated with phosphorylated adducin or due to reduction of endogenous adducin

  5. Results of this study provide evidence for a role for spectrin in different steps of megakaryocyte development through its participation in the formation of invaginated membranes and in the maintenance of proplatelet structure.

  6. Analysis of 3 new alleles reveals previously unknown consequences of red blood cell (RBC (show CACNA1C ELISA Kits)) spectrin deficiency, resulting in markedly reduced RBC (show CACNA1C ELISA Kits) membrane spectrin content, decreased band 3 (show SLC4A1 ELISA Kits), and absent beta-adducin (show ADD2 ELISA Kits).

  7. Murine recessive hereditary spherocytosis, sph/sph (show NUMA1 ELISA Kits), is caused by a mutation in the erythroid alpha-spectrin gene.

Human Spectrin alpha 1, Erythrocytic (SPTA1) interaction partners

  1. A novel SPTA1 mutation (H54P) was identified in a case of hereditary elliptocytosis.

  2. The authors show that SUB1-mediated processing of MSP1 is important for parasite viability, the processing modifies the secondary structure of MSP1 and activates its capacity to bind spectrin.

  3. The authors demonstrate that the initial vacuolar membrane around internalized Babesia divergens is formed from protein and lipid components of the red blood cells plasma membrane, including band 3, glycophorin A and spectrin.

  4. a new function for spectrins in the stability of invadosomes and the coupling between actin regulation and ECM (show MMRN1 ELISA Kits) degradation

  5. Case Report: severe hemolytic jaundice and a phenotype of hereditary spherocytosis due alpha-spectrin (show SPTAN1 ELISA Kits) mutations.

  6. In this review, we summarize the state of knowledge about interactions between spectrin and membrane lipids

  7. A novel exon 2 alpha spectrin (show SPTAN1 ELISA Kits) mutation is identified in two families of European ancestry with hereditary pyropoikilocytosis.

  8. The heterozygous c.121C>T mutation of SPTA1 gene induces an amino acid change p.Arg41Trp in the alpha1 domain of the alpha-spectrin (show SPTAN1 ELISA Kits) protein.

  9. Data show that transcription cofactor TAF3 (show TAF3 ELISA Kits) is required for transcription of the alpha spectrin (show SPTAN1 ELISA Kits) SPTA1 gene.

  10. The common hereditary elliptocytosis-associated alpha-spectrin leucine260proline mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation.

Spectrin alpha 1, Erythrocytic (SPTA1) Antigen Profile

Antigen Summary

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.

Alternative names and synonyms associated with Spectrin alpha 1, Erythrocytic (SPTA1)

  • spectrin, alpha, erythrocytic 1 (elliptocytosis 2) (Spta1) Elisa Kit
  • spectrin alpha, erythrocytic 1 (Spta1) Elisa Kit
  • spectrin, alpha, erythrocytic 1 (elliptocytosis 2) (SPTA1) Elisa Kit
  • AF093576 Elisa Kit
  • AI451697 Elisa Kit
  • EL2 Elisa Kit
  • ha Elisa Kit
  • HPP Elisa Kit
  • HS3 Elisa Kit
  • ihj Elisa Kit
  • nmf4 Elisa Kit
  • sph Elisa Kit
  • SPH3 Elisa Kit
  • Spna-1 Elisa Kit
  • Spna1 Elisa Kit
  • SPTA Elisa Kit

Protein level used designations for SPTA1

erythroid spectrin alpha , spectrin alpha chain, erythrocyte , alpha-spectrin 1, erythroid , erythroid alpha-spectrin , hemolytic anemia , neuroscience mutagenesis facility, 4 , spectrin alpha 1 , spectrin alpha chain, erythrocytic 1 , spherocytosis , alpha-I spectrin

289257 Rattus norvegicus
20739 Mus musculus
6708 Homo sapiens
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