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PAS Domain Containing Serine/threonine Kinase ELISA Kits (PASK)
On www.antibodies-online.com are 2 PAS Domain Containing Serine/threonine Kinase (PASK) ELISA Kits from 1 different suppliers available. Additionally we are shipping PASK Antibodies (26) and PASK Proteins (6) and many more products for this protein. A total of 35 PASK products are currently listed.
Synonyms:
mKIAA0135, pas, PASK, PASKIN, STK37, wu:fb69h07
list all ELISA KIts Gene Name GeneID UniProt
Rat PASK PASK 301617  
PASK 23178 Q96RG2
PASK 269224 Q8CEE6

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More ELISA Kits for PASK Interaction Partners

Human PAS Domain Containing Serine/threonine Kinase (PASK) interaction partners

  1. PASK phosphorylates and inactivates GSK3beta (show GSK3b ELISA Kits), thereby preventing PDX-1 (show PDX1 ELISA Kits) serine phosphorylation and alleviating GSK3beta (show GSK3b ELISA Kits)-mediated PDX-1 (show PDX1 ELISA Kits) protein degradation in pancreatic beta-cells.

  2. Mutations that affect PAS domain cause a severe protein trafficking defect and change the interactions with Kv11.1 (show KCNH2 ELISA Kits) channels.

  3. The role of PAS kinase in PASsing the glucose signal.

  4. Per-Arnt (show ARNT ELISA Kits)-Sim (show SIM2 ELISA Kits) (PAS) domain-containing protein kinase (show CDK7 ELISA Kits) (PASK) has a role in insulin (show INS ELISA Kits) hypersecretion

  5. PASK is involved in the regulation of glucagon (show GCG ELISA Kits) secretion by glucose and may be a useful target for the treatment of type 2 diabetes.

  6. Structural bases of PAS domain-regulated kinase (PASK) activation in the absence of activation loop phosphorylation.

  7. Results suggest that elevated glucose concentrations rapidly increase Per-Arnt (show ARNT ELISA Kits)-Sim (show SIM2 ELISA Kits) kinase activity in pancreatic islet beta cells, followed by up-regulation by glucose of preproinsulin (show INS ELISA Kits) and pancreatic duodenum homeobox (show Lbx1 ELISA Kits) 1 gene expression.

  8. identified the multifunctional eukaryotic translation elongation factor (show TSFM ELISA Kits) eEF1A1 (show EEF1A1 ELISA Kits) as a novel interaction partner of PASKIN in the nuclei of testis germ cells and in the midpiece of sperm tails

Mouse (Murine) PAS Domain Containing Serine/threonine Kinase (PASK) interaction partners

  1. The findings demonstrate cell-autonomous roles for PASK in the control of pancreatic endocrine hormone secretion. Differences between the glycaemic phenotype of global vs cell type-specific null mice suggest important roles for tissue interactions in the control of glycaemia by PASK.

  2. the PAS kinase function could be critical for preserving the nutrient effect on AMP-activated protein kinase (show PRKAA2 ELISA Kits) and mammalian target of rapamycin (show FRAP1 ELISA Kits)/S6K1 (show RPS6KB1 ELISA Kits) pathways and maintain the regulatory role of exendin-4 in food intake

  3. PASK is a key kinase in GLP-1 (show GCG ELISA Kits) actions and exerts a coordinated response with the other metabolic sensors.

  4. PASK phosphorylates and inactivates GSK3beta (show GSK3b ELISA Kits), thereby preventing PDX-1 (show PDX1 ELISA Kits) serine phosphorylation and alleviating GSK3beta (show GSK3b ELISA Kits)-mediated PDX-1 (show PDX1 ELISA Kits) protein degradation in pancreatic beta-cells.

  5. These data strongly suggest that PASK is required for normal nutrient partitioning and energy homeostasis in the mouse and that this activity is primarily carried out in a cell-autonomous fashion.[Review]

  6. PASK is involved in the regulation of glucagon (show GCG ELISA Kits) secretion by glucose and may be a useful target for the treatment of type 2 diabetes.

  7. Targeted disruption of the PAS domain serine/threonine kinase was studied.

  8. Paskin gene expression is not induced by glucose in pancreatic beta-cells and glucose-stimulated insulin (show INS ELISA Kits) production is independent of PASKIN.

  9. PASK acts in a cell-autonomous manner to maintain cellular energy homeostasis and is a potential therapeutic target for metabolic disease

  10. Suggest that paskin is involved in the central control of hypoxic ventilation, modulating ventilation in a gender-dependent manner.

PASK Antigen Profile

Antigen Summary

This gene encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with PASK

  • PAS domain containing serine/threonine kinase (Pask) Elisa Kit
  • PAS domain containing serine/threonine kinase (pask) Elisa Kit
  • PAS domain containing serine/threonine kinase (PASK) Elisa Kit
  • mKIAA0135 Elisa Kit
  • pas Elisa Kit
  • PASK Elisa Kit
  • PASKIN Elisa Kit
  • STK37 Elisa Kit
  • wu:fb69h07 Elisa Kit

Protein level used designations for PASK

PAS domain-containing serine/threonine-protein kinase , PAS domain containing serine/threonine kinase , PAS domain-containing serine/threonine-protein kinase-like , per-arnt-sim (PAS) domain kinase , PAS-kinase , paskin

GENE ID SPECIES
301617 Rattus norvegicus
322674 Danio rerio
424845 Gallus gallus
460077 Pan troglodytes
512154 Bos taurus
609502 Canis lupus familiaris
100067612 Equus caballus
100390748 Callithrix jacchus
100454642 Pongo abelii
23178 Homo sapiens
269224 Mus musculus
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