Browse our anti-Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) Antibodies

Full name:
anti-Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Antibodies (PPP1R9B)
On www.antibodies-online.com are 49 Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) Antibodies from 11 different suppliers available. Additionally we are shipping Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Kits (9) and Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Proteins (4) and many more products for this protein. A total of 63 Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin products are currently listed.
Synonyms:
Neb2, PPP1R6, PPP1R9, SPINO, SPL, Spn
list all antibodies Gene Name GeneID UniProt
PPP1R9B 84686 O35274
PPP1R9B 84687 Q96SB3
PPP1R9B 217124 Q6R891

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Most Popular Reactivities for anti-Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) Antibodies

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Top referenced anti-Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Antibodies

  1. Human Polyclonal PPP1R9B Primary Antibody for EIA, WB - ABIN953658 : Sagara, Kawasaki, Iemura, Natsume, Takai, Akiyama: Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration. in Oncogene 2009 (PubMed)
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More Antibodies against Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Interaction Partners

Human Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) interaction partners

  1. Data identify Spn (show SPN Antibodies) as a critical adhesion and signaling protein that is essential for modulating glioblastoma cell invasion in the brain microenvironment. Spn (show SPN Antibodies) suppresses brain tumor cell invasion, in part, via control of Rac1 GTPase (show RACGAP1 Antibodies) activities and invadopodia disassembly. Its C-terminus binds directly to the beta 8 integrin cytoplasmic tail.

  2. results indicate that spinophilin plays an important role in regulating the activity of Group I mGluRs as well as their influence on synaptic activity.

  3. Low spinophilin expression enhances aggressive biological behavior of breast cancer.

  4. Colorectal carcinoma expression of spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance.

  5. spinophilin might play a previously unrecognized role in the pathogenesis of head and neck squamous cell carcinoma

  6. Spn (show SPN Antibodies) downregulation contributes to a more aggressive biologic behavior, induces chemoresistance, and is associated with a poorer survival in patients with advanced stages of colorectal carcinoma.

  7. study found a substantial number of hepatocellular carcinomas (HCC (show FAM126A Antibodies)) show reduced or absent Spn (show SPN Antibodies) expression; the low expression of Spn (show SPN Antibodies) in tumour tissue is an independent negative prognostic factor for clinical outcome in HCC (show FAM126A Antibodies); spinophilin expression inversely correlates with proliferative activity

  8. Studies suggest that any change in substrate specificity of the spinophilin : PP1 (show PPA1 Antibodies) holoenzyme complex was probably due to direct modification of a PP1 (show PPA1 Antibodies) substrate binding surface.

  9. Spinophilin associates with both delta- and mu-OmicronR and G protein subunits in HEK293 cells participating in a multimeric signaling complex that displays a differential regulatory role in opioid receptor signaling.

  10. Spinophilin-deficient mice have enhanced antidepressant response to desipramine compared with wild-type controls.

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) interaction partners

  1. two homologs neurabin and spinophilin play important yet distinct roles in the regulation of anxiety- and depression-like behaviors in an age-dependent manner.

  2. results indicate that spinophilin plays an important role in regulating the activity of Group I mGluRs as well as their influence on synaptic activity.

  3. COPS5 (show COPS5 Antibodies) overexpression reduced spinophilin in both the cortex (19%, p < 0.05) and the hippocampus (20%, p < 0.05), leading to significant deficits in learning and memory skills

  4. RanBP9 (show RANBP9 Antibodies) overexpression in transgenic mice led to striking reduction in the levels of spinophilin.

  5. Canonical betaAR-mediated signaling coupled to PKA activation results in phosphorylation of spinophilin, disrupting its interaction with alpha2AARs and accelerating alpha2AAR (show ADRA2A Antibodies) endocytic responses.

  6. Findings support the concept that the inhibitory effects of SPL (show SGPL1 Antibodies) on M3R (show CHRM3 Antibodies) activity are mediated by RGS4 (show RGS4 Antibodies).

  7. changes in spinophilin/CaMKII (show CAMK2G Antibodies) interactomes may contribute to changes in striatal dendritic spine density, morphology, and function during normal postnatal maturation and aging.

  8. these data suggest that spinophilin is an upstream regulator required for normal growth and excitation-contraction coupling, but is dispensable for beta-adrenergic stimulation of adult cardiomyocytes.

  9. Findings suggest that spinophilin restrains Angiotensin II-mediated sympathetic nervous system activation and is an unrecognized molecule with regard to central blood pressure control

  10. We suggest that Spn (show SPN Antibodies) may be the tumor suppressor gene located at 17q21.33 acting through Rb regulation.

Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) Antigen Profile

Antigen Summary

Spinophilin is a regulatory subunit of protein phosphatase-1 catalytic subunit (PP1\; see MIM 176875) and is highly enriched in dendritic spines, specialized protrusions from dendritic shafts that receive most of the excitatory input in the central nervous system (Allen et al., 1997

Alternative names and synonyms associated with Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B)

  • protein phosphatase 1, regulatory subunit 9B (Ppp1r9b) antibody
  • protein phosphatase 1, regulatory subunit 9B (PPP1R9B) antibody
  • Neb2 antibody
  • PPP1R6 antibody
  • PPP1R9 antibody
  • SPINO antibody
  • SPL antibody
  • Spn antibody

Protein level used designations for PPP1R9B

PP1bp134 , neurabin 2 , neurabin-2 , neurabin-II , neural tissue-specific F-actin-binding protein II , nuerabin 2 , p130 , spinophilin , neurabin II , protein phosphatase 1, regulatory (inhibitor) subunit 9B , protein phosphatase 1, regulatory subunit 9B, spinophilin

GENE ID SPECIES
84686 Rattus norvegicus
84687 Homo sapiens
217124 Mus musculus
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