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Browse our anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) Antibodies

Full name:
anti-STIP1 Homology and U-Box Containing Protein 1 Antibodies (STUB1)
On www.antibodies-online.com are 113 STIP1 Homology and U-Box Containing Protein 1 (STUB1) Antibodies from 22 different suppliers available. Additionally we are shipping STIP1 Homology and U-Box Containing Protein 1 Proteins (21) and STIP1 Homology and U-Box Containing Protein 1 Kits (15) and many more products for this protein. A total of 156 STIP1 Homology and U-Box Containing Protein 1 products are currently listed.
Synonyms:
0610033N24Rik, 2210017D18Rik, 2310040B03Rik, ATCHIP, AW046544, carboxyl terminus of HSC70-interacting protein, CHIP, HSPABP2, NY-CO-7, SDCCAG7, STUB1, UBOX1, wu:fc22f04, zgc:56076
list all antibodies Gene Name GeneID UniProt
STUB1 56424 Q9WUD1
STUB1 10273 Q9UNE7
STUB1 287155  

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All available anti-STIP1 Homology and U-Box Containing Protein 1 Antibodies

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Top referenced anti-STIP1 Homology and U-Box Containing Protein 1 Antibodies

  1. Human Polyclonal STUB1 Primary Antibody for EIA, IHC (p) - ABIN359012 : Peng, Morishima, Jenkins, Dunbar, Lau, Patterson, Pratt, Osawa: Ubiquitylation of neuronal nitric-oxide synthase by CHIP, a chaperone-dependent E3 ligase. in The Journal of biological chemistry 2004 (PubMed)
    Show all 10 references for ABIN359012

  2. Human Polyclonal STUB1 Primary Antibody for EIA, FACS - ABIN954992 : Stankiewicz, Nikolay, Rybin, Mayer: CHIP participates in protein triage decisions by preferentially ubiquitinating Hsp70-bound substrates. in The FEBS journal 2010 (PubMed)
    Show all 3 references for ABIN954992

  3. Human Polyclonal STUB1 Primary Antibody for IP, PLA - ABIN262267 : Tsvetkov, Adamovich, Elliott, Shaul: E3 ligase STUB1/CHIP regulates NAD(P)H:quinone oxidoreductase 1 (NQO1) accumulation in aged brain, a process impaired in certain Alzheimer disease patients. in The Journal of biological chemistry 2011 (PubMed)
    Show all 2 references for ABIN262267

  4. Cow (Bovine) Polyclonal STUB1 Primary Antibody for EIA, WB - ABIN374173 : Jiang, Ballinger, Wu, Dai, Cyr, Höhfeld, Patterson: CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation. in The Journal of biological chemistry 2001 (PubMed)

  5. Chicken Polyclonal STUB1 Primary Antibody for IHC, WB - ABIN2774916 : Parsons, Tait, Finch, Dianova, Allinson, Dianov: CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins. in Molecular cell 2008 (PubMed)

More Antibodies against STIP1 Homology and U-Box Containing Protein 1 Interaction Partners

Arabidopsis thaliana STIP1 Homology and U-Box Containing Protein 1 (STUB1) interaction partners

  1. Through selective degradation of Clp subunits, AtCHIP could positively regulate homeostasis of Clp proteolytic subunits and maximize the production of functional chloroplasts. Similar results were obtained from transgenic tobacco plants.

  2. we propose that CHIP and NBR1 (show NBR1 Antibodies) mediate two distinct but complementary anti-proteotoxic pathways and protein's propensity to aggregate under stress conditions is one of the critical factors for pathway selection of protein degradation

  3. Hsc70-4 and CHIP were highly induced in ppi2 mutant plants, where they mediated the degradation of chloroplast-targeted precursors through the ubiquitin-26S proteasome (show Psmd4 Antibodies) system.

  4. AtCHIP, an E3 ubiquitin liagase, functions upstream of protein phosphatase 2A in stress-responsive signal transduction pathways under conditions of low temperature or in the dark. [AtCHIP]

  5. The interaction of CHIP with FtsH1 in vitro, in normal and in CHIP-over-expressing plants is reported.

Mouse (Murine) STIP1 Homology and U-Box Containing Protein 1 (STUB1) interaction partners

  1. The chaperone protein Hsp70 (show HSP70 Antibodies) was found to be important for CHIP and NUCB1 (show NUCB1 Antibodies) interaction as well as CHIP-mediated NUCB1 (show NUCB1 Antibodies) down-regulation.

  2. CHIP is a negative regulator of RIPK1 (show RIPK1 Antibodies) and RIPK3 (show RIPK3 Antibodies), thus inhibiting necroptosis.

  3. our study demonstrated that over-expressing miR (show MLXIP Antibodies)-21 in UCBMSCs could improve neovascularization in Critical limb ischemia (CLI (show CLU Antibodies)) through enhancing HIF-1alpha (show HIF1A Antibodies) activity by targeting CHIP, which may hold great therapeutic promise in treating CLI (show CLU Antibodies)

  4. PABPN1 (show PABPN1 Antibodies) interacts with and is stabilized by heat shock protein 90 (show HSP90 Antibodies).

  5. CHIP targets Osx (show SP7 Antibodies) for ubiquitination and degradation in osteoblasts after chronic exposure to TNF-alpha (show TNF Antibodies).

  6. CHIP/TRAF3 (show TRAF3 Antibodies)/NIK (show MAP4K4 Antibodies) interactions recruit NIK (show MAP4K4 Antibodies) to E3 ligase complexes for ubiquitination and degradation, thus maintaining NIK (show MAP4K4 Antibodies) at low levels

  7. Cbl-b, together with Stub1, ubiquitinate Foxp3 (show FOXP3 Antibodies), and regulate tTreg development.

  8. CHIP regulates the levels of FMR1 (show FMR1 Antibodies) as an E3 ubiquitin ligase (show MUL1 Antibodies) in phosphorylation-dependent manner, suggesting that CHIP regulates FMR1 (show FMR1 Antibodies)-mediated translational repression by regulating the levels of FMR1 (show FMR1 Antibodies).

  9. The cardiac CHIP appears to play a role in regulating autophagy during the development of cardiac hypertrophy, possibly by its role in supporting Akt (show AKT1 Antibodies) signalling, induced by voluntary running in vivo.

  10. Ebp1 (show NFKB1 Antibodies) p42 (show EPB42 Antibodies) isoform regulates the proteasomal degradation of the p85 (show ECM1 Antibodies) regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70 (show HSP70 Antibodies)/CHIP.

Human STIP1 Homology and U-Box Containing Protein 1 (STUB1) interaction partners

  1. Data show that BAG2 (show BAG2 Antibodies) Inhibits CHIP-Mediated HSP72 (show HSPA1A Antibodies) ubiquitination in aged cells.

  2. Data show that transcription factor regulatory factor X 1 (RFX1 (show RFX1 Antibodies)) protein expression can be tightly regulated by polyubiquitination-mediated proteosomal degradation via STIP1 homology and U-box containing protein 1 (STUB1).

  3. CHIP may serve as a promising prognostic biomarker for non-small cell lung cancer (NSCLC] patients and it may be involved in NSCLC angiogenesis through regulating VEGF (show VEGFA Antibodies) secretion and expression of VEGFR2 (show KDR Antibodies).

  4. Cdk5 (show CDK5 Antibodies)-mediated phosphorylation of CHIP negatively regulates its neuroprotective function, thereby contributing to neuronal cell death progression following neurotoxic stimuli.

  5. CHIP is a bona fide negative regulator of the RIPK1 (show RIPK1 Antibodies)-RIPK3 (show RIPK3 Antibodies) necrosome formation leading to desensitization of TNF (show TNF Antibodies)-mediated necroptosis

  6. Protein-protein interactions modulate the docking-dependent E3-ubiquitin ligase (show MUL1 Antibodies) activity of CHIP.

  7. Data show that the E3 ubiquitin ligase (show MUL1 Antibodies) CHIP interacts with protein arginine methyltransferase-5 (PRMT5 (show PRMT5 Antibodies)) both in vivo and in vitro.

  8. These results indicate that CHIP decreases the Kv1.5 (show KCNA5 Antibodies) protein level and functional channel by facilitating its degradation in concert with chaperone Hsc70 (show HSPA8 Antibodies)

  9. detailed and systematic investigation to characterize if there are significant differences in the CHIP in vitro ubiquitination of human Hsp70 (show HSP70 Antibodies) and Hsc70 (show HSPA8 Antibodies).

  10. CHIP stabilizes amyloid precursor protein (show APP Antibodies) via proteasomal degradation and p53 (show TP53 Antibodies)-mediated trans-repression of BACE1 (show BACE Antibodies).

STIP1 Homology and U-Box Containing Protein 1 (STUB1) Antigen Profile

Antigen Summary

STUB1, or CHIP, is a ubiquitin ligase/cochaperone that participates in protein quality control by targeting a broad range of chaperone protein substrates for degradation (Min et al., 2008

Alternative names and synonyms associated with STIP1 Homology and U-Box Containing Protein 1 (STUB1)

  • STIP1 homology and U-box containing protein 1 (STUB1) antibody
  • STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase (stub1) antibody
  • STIP1 homology and U box-containing protein 1 (LOC100282870) antibody
  • E3 ubiquitin-protein ligase CHIP (CHIP) antibody
  • SET domain containing 1B (SETD1B) antibody
  • STIP1 homology and U-Box containing protein 1 (Stub1) antibody
  • STIP1 homology and U-Box containing protein 1 (stub1) antibody
  • STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase (STUB1) antibody
  • STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase (Stub1) antibody
  • 0610033N24Rik antibody
  • 2210017D18Rik antibody
  • 2310040B03Rik antibody
  • ATCHIP antibody
  • AW046544 antibody
  • carboxyl terminus of HSC70-interacting protein antibody
  • CHIP antibody
  • HSPABP2 antibody
  • NY-CO-7 antibody
  • SDCCAG7 antibody
  • STUB1 antibody
  • UBOX1 antibody
  • wu:fc22f04 antibody
  • zgc:56076 antibody

Protein level used designations for STUB1

STIP1 homology and U-box containing protein 1 , STIP1 homology and U box-containing protein 1 , E3 ubiquitin-protein ligase CHIP , carboxy terminus of Hsp70-interacting protein , CHIP , CLL-associated antigen KW-8 , antigen NY-CO-7 , heat shock protein A binding protein 2 (c-terminal) , serologically defined colon cancer antigen 7 , STIP1 homology and U-Box containing protein 1

GENE ID SPECIES
453803 Pan troglodytes
479892 Canis lupus familiaris
697105 Macaca mulatta
779800 Xenopus (Silurana) tropicalis
100282870 Zea mays
819925 Arabidopsis thaliana
514102 Bos taurus
56424 Mus musculus
324243 Danio rerio
10273 Homo sapiens
287155 Rattus norvegicus
733415 Xenopus laevis
426918 Gallus gallus
504565 Bos taurus
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