Browse our anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) Antibodies

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anti-STIP1 Homology and U-Box Containing Protein 1 Antibodies (STUB1)
On www.antibodies-online.com are 115 STIP1 Homology and U-Box Containing Protein 1 (STUB1) Antibodies from 23 different suppliers available. Additionally we are shipping STIP1 Homology and U-Box Containing Protein 1 Proteins (20) and STIP1 Homology and U-Box Containing Protein 1 Kits (18) and many more products for this protein. A total of 160 STIP1 Homology and U-Box Containing Protein 1 products are currently listed.
Synonyms:
0610033N24Rik, 2210017D18Rik, 2310040B03Rik, ATCHIP, AW046544, carboxyl terminus of HSC70-interacting protein, CHIP, HSPABP2, NY-CO-7, SDCCAG7, STUB1, UBOX1, wu:fc22f04, zgc:56076
list all antibodies Gene Name GeneID UniProt
STUB1 56424 Q9WUD1
STUB1 10273 Q9UNE7
STUB1 287155  

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Top referenced anti-STIP1 Homology and U-Box Containing Protein 1 Antibodies

  1. Human Polyclonal STUB1 Primary Antibody for IP, PLA - ABIN262267 : Tsvetkov, Adamovich, Elliott, Shaul: E3 ligase STUB1/CHIP regulates NAD(P)H:quinone oxidoreductase 1 (NQO1) accumulation in aged brain, a process impaired in certain Alzheimer disease patients. in The Journal of biological chemistry 2011 (PubMed)
    Show all 2 references for 262267

  2. Cow (Bovine) Polyclonal STUB1 Primary Antibody for IHC, WB - ABIN2774916 : Parsons, Tait, Finch, Dianova, Allinson, Dianov: CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins. in Molecular cell 2008 (PubMed)

  3. Human Polyclonal STUB1 Primary Antibody for ELISA, WB - ABIN184697 : Jiang, Ballinger, Wu, Dai, Cyr, Höhfeld, Patterson: CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation. in The Journal of biological chemistry 2001 (PubMed)

More Antibodies against STIP1 Homology and U-Box Containing Protein 1 Interaction Partners

Arabidopsis thaliana STIP1 Homology and U-Box Containing Protein 1 (STUB1) interaction partners

  1. Through selective degradation of Clp subunits, AtCHIP could positively regulate homeostasis of Clp proteolytic subunits and maximize the production of functional chloroplasts. Similar results were obtained from transgenic tobacco plants.

  2. we propose that CHIP and NBR1 (show NBR1 Antibodies) mediate two distinct but complementary anti-proteotoxic pathways and protein's propensity to aggregate under stress conditions is one of the critical factors for pathway selection of protein degradation

  3. Hsc70-4 and CHIP were highly induced in ppi2 mutant plants, where they mediated the degradation of chloroplast-targeted precursors through the ubiquitin-26S proteasome (show Psmd4 Antibodies) system.

  4. AtCHIP, an E3 ubiquitin liagase, functions upstream of protein phosphatase 2A in stress-responsive signal transduction pathways under conditions of low temperature or in the dark. [AtCHIP]

  5. The interaction of CHIP with FtsH1 in vitro, in normal and in CHIP-over-expressing plants is reported.

Mouse (Murine) STIP1 Homology and U-Box Containing Protein 1 (STUB1) interaction partners

  1. ACR (show ACR Antibodies) interacts with proteins that regulate the ubiquitin-proteasome system, predominantly with the E3 ubiquitin-protein ligases Stub1, which binds the NH2 terminus of the ACR (show ACR Antibodies), and CRL4(CRBN (show CRBN Antibodies)), which is formed by Cul4a (show CUL4A Antibodies)/b, Ddb1 (show DDB1 Antibodies), and Crbn (show CRBN Antibodies), and interacts with the COOH terminus of the ACR (show ACR Antibodies) via Crbn (show CRBN Antibodies).

  2. The chaperone protein Hsp70 (show HSP70 Antibodies) was found to be important for CHIP and NUCB1 (show NUCB1 Antibodies) interaction as well as CHIP-mediated NUCB1 (show NUCB1 Antibodies) down-regulation.

  3. CHIP is a negative regulator of RIPK1 (show RIPK1 Antibodies) and RIPK3 (show RIPK3 Antibodies), thus inhibiting necroptosis.

  4. our study demonstrated that over-expressing miR (show MLXIP Antibodies)-21 in UCBMSCs could improve neovascularization in Critical limb ischemia (CLI (show CLU Antibodies)) through enhancing HIF-1alpha (show HIF1A Antibodies) activity by targeting CHIP, which may hold great therapeutic promise in treating CLI (show CLU Antibodies)

  5. PABPN1 (show PABPN1 Antibodies) interacts with and is stabilized by heat shock protein 90 (show HSP90 Antibodies).

  6. CHIP targets Osx (show SP7 Antibodies) for ubiquitination and degradation in osteoblasts after chronic exposure to TNF-alpha (show TNF Antibodies).

  7. CHIP/TRAF3 (show TRAF3 Antibodies)/NIK (show MAP4K4 Antibodies) interactions recruit NIK (show MAP4K4 Antibodies) to E3 ligase complexes for ubiquitination and degradation, thus maintaining NIK (show MAP4K4 Antibodies) at low levels

  8. Cbl-b, together with Stub1, ubiquitinate Foxp3 (show FOXP3 Antibodies), and regulate tTreg development.

  9. CHIP regulates the levels of FMR1 (show FMR1 Antibodies) as an E3 ubiquitin ligase (show MUL1 Antibodies) in phosphorylation-dependent manner, suggesting that CHIP regulates FMR1 (show FMR1 Antibodies)-mediated translational repression by regulating the levels of FMR1 (show FMR1 Antibodies).

  10. The cardiac CHIP appears to play a role in regulating autophagy during the development of cardiac hypertrophy, possibly by its role in supporting Akt (show AKT1 Antibodies) signalling, induced by voluntary running in vivo.

Human STIP1 Homology and U-Box Containing Protein 1 (STUB1) interaction partners

  1. we report the identification of an unconventional p14ARF (show CDKN2A Antibodies) degradation pathway induced by the chaperone HSP90 (show HSP90 Antibodies) in association with the E3 ubiquitin ligase (show MUL1 Antibodies) C-terminus of HSP70-interacting protein (show HSPBP1 Antibodies) (CHIP).

  2. C terminus of Hsc70-interacting protein (show ST13 Antibodies) (CHIP) selectively interacted with epidermal growth factor receptor (EGFR (show EGFR Antibodies)) mutants and simultaneously induced their ubiquitination and proteasomal degradation.

  3. Study reveals an important function of CHIP-mediated proteolysis in insulin (show INS Antibodies) and IGF1 (show IGF1 Antibodies) signaling; upon proteotoxic stress conditions and during aging, CHIP is recruited toward disposal of misfolded proteins, reducing its capacity to degrade the INSR (show INSR Antibodies); identify a degradation pathway that controls the level of active DAF-2 (show INSR Antibodies)/INSR (show INSR Antibodies) in C. elegans, Drosophila and human cells.

  4. Overexpression of CHIP decreased intracellular protein (show CKAP2 Antibodies) levels of both G2385R mutant and wild-type LRRK2 (show LRRK2 Antibodies), while short interfering RNA CHIP knockdown had the opposite effect

  5. CHIP directly regulates the stability of CD166 protein through the ubiquitin proteasome system.

  6. Data show that BAG2 (show BAG2 Antibodies) Inhibits CHIP-Mediated HSP72 (show HSPA1A Antibodies) ubiquitination in aged cells.

  7. Data show that transcription factor regulatory factor X 1 (RFX1 (show RFX1 Antibodies)) protein expression can be tightly regulated by polyubiquitination-mediated proteosomal degradation via STIP1 homology and U-box containing protein 1 (STUB1).

  8. CHIP may serve as a promising prognostic biomarker for non-small cell lung cancer (NSCLC] patients and it may be involved in NSCLC angiogenesis through regulating VEGF (show VEGFA Antibodies) secretion and expression of VEGFR2 (show KDR Antibodies).

  9. Cdk5 (show CDK5 Antibodies)-mediated phosphorylation of CHIP negatively regulates its neuroprotective function, thereby contributing to neuronal cell death progression following neurotoxic stimuli.

  10. CHIP is a bona fide negative regulator of the RIPK1 (show RIPK1 Antibodies)-RIPK3 (show RIPK3 Antibodies) necrosome formation leading to desensitization of TNF (show TNF Antibodies)-mediated necroptosis

STIP1 Homology and U-Box Containing Protein 1 (STUB1) Antigen Profile

Antigen Summary

STUB1, or CHIP, is a ubiquitin ligase/cochaperone that participates in protein quality control by targeting a broad range of chaperone protein substrates for degradation (Min et al., 2008

Alternative names and synonyms associated with STIP1 Homology and U-Box Containing Protein 1 (STUB1)

  • STIP1 homology and U-box containing protein 1 (STUB1) antibody
  • STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase (stub1) antibody
  • STIP1 homology and U box-containing protein 1 (LOC100282870) antibody
  • E3 ubiquitin-protein ligase CHIP (CHIP) antibody
  • SET domain containing 1B (SETD1B) antibody
  • STIP1 homology and U-Box containing protein 1 (Stub1) antibody
  • STIP1 homology and U-Box containing protein 1 (stub1) antibody
  • STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase (STUB1) antibody
  • STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase (Stub1) antibody
  • 0610033N24Rik antibody
  • 2210017D18Rik antibody
  • 2310040B03Rik antibody
  • ATCHIP antibody
  • AW046544 antibody
  • carboxyl terminus of HSC70-interacting protein antibody
  • CHIP antibody
  • HSPABP2 antibody
  • NY-CO-7 antibody
  • SDCCAG7 antibody
  • STUB1 antibody
  • UBOX1 antibody
  • wu:fc22f04 antibody
  • zgc:56076 antibody

Protein level used designations for STUB1

STIP1 homology and U-box containing protein 1 , STIP1 homology and U box-containing protein 1 , E3 ubiquitin-protein ligase CHIP , carboxy terminus of Hsp70-interacting protein , CHIP , CLL-associated antigen KW-8 , antigen NY-CO-7 , heat shock protein A binding protein 2 (c-terminal) , serologically defined colon cancer antigen 7 , STIP1 homology and U-Box containing protein 1

GENE ID SPECIES
453803 Pan troglodytes
479892 Canis lupus familiaris
697105 Macaca mulatta
779800 Xenopus (Silurana) tropicalis
100282870 Zea mays
819925 Arabidopsis thaliana
514102 Bos taurus
56424 Mus musculus
324243 Danio rerio
10273 Homo sapiens
287155 Rattus norvegicus
733415 Xenopus laevis
426918 Gallus gallus
504565 Bos taurus
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