Browse our HOP Homeobox Proteins (HOPX)

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HOP Homeobox Proteins (HOPX)
On are 18 HOP Homeobox (HOPX) Proteins from 7 different suppliers available. Additionally we are shipping HOP Homeobox Antibodies (64) and many more products for this protein. A total of 86 HOP Homeobox products are currently listed.
1110018K11Rik, 1200015P04Rik, 2300002F06Rik, AI848177, AW490897, Cameo, GIIg15b, Hdop, Hod, Hop, HOPX, LAGY, MGC147344, NECC1, Ob1, Obl, SMAP31, Toto
list all proteins Gene Name GeneID UniProt
HOPX 84525 Q9BPY8
HOPX 74318 Q8R1H0
HOPX 171160 Q78ZR5

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HOP Homeobox Proteins (HOPX) by Origin

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Top referenced HOP Homeobox Proteins

  1. Human HOPX Protein expressed in Escherichia coli (E. coli) - ABIN1686718 : Flom, Behal, Rosen, Cole, Johnson: Definition of the minimal fragments of Sti1 required for dimerization, interaction with Hsp70 and Hsp90 and in vivo functions. in The Biochemical journal 2007 (PubMed)
    Show all 5 references for 1686718

  2. Human HOPX Protein expressed in Escherichia coli (E. coli) - ABIN1098644 : Adu, Leong, Smith, Leek, Markham, Robinson, Mighell: Expression of mOb1, a novel atypical 73 amino acid K50-homeodomain protein, during mouse development. in Mechanisms of development 2003 (PubMed)
    Show all 2 references for 1098644

More Proteins for HOP Homeobox Interaction Partners

Human HOP Homeobox (HOPX) interaction partners

  1. HOPX promoter methylation is not only frequent and cancer-specific but also associated with aggressive phenotype in breast cancer.

  2. Computational results identified HOPX gene as a new potential driver for ovarian carcinogenesis.

  3. The results suggest that HOPX may contribute to pathogenesis or manifestation of hypertrophic cardiomyopathy as a modifier gene.

  4. Data show that binding of heat shock proteins Hsp70 (show HSP70 Proteins) and Hsp90 (show HSP90 Proteins) requires prior binding of Hop (show STIP1 Proteins) protein to Hsp90 (show HSP90 Proteins).

  5. HOPX is methylated and exerts tumour-suppressive function through Ras-induced senescence in human lung cancer.

  6. GATA6 (show GATA6 Proteins) and HOPX are critical nodes in a lineage-selective pathway that directly links effectors of airway epithelial specification to the inhibition of metastasis in the lung ADC (show ADC Proteins) subtype.

  7. HOPX-beta promoter methylation is a frequent and cancer-specific event in CRC (show CALR Proteins) progression.

  8. Knockdown of Hop (show STIP1 Proteins) caused a decrease in the level of RhoC GTPase (show RHOC Proteins), and significantly inhibited pseudopodia formation in Hs578T cells. Our data suggest that Hop (show STIP1 Proteins) regulates directional cell migration by multiple unknown mechanisms.

  9. HOPX/Hopx expression is reduced in multiple examples of human and murine cardiac hypertrophy and failure.

  10. results identify distinct functions for the Hop (show STIP1 Proteins) cochaperone, revealing an asymmetric mechanism for Hsp90 (show HSP90 Proteins) regulation and client loading

Mouse (Murine) HOP Homeobox (HOPX) interaction partners

  1. Analysis of the hematopoietic stem/progenitor cell pool in Hopx-/- mice demonstrated significantly reduced cell frequencies and impaired engraftment in competitive repopulation assays, thus providing functional validation of this positional candidate gene

  2. Type I alveolar cells expressing Hopx manifest plasticity to regenerate type II alveolar cells in the lung.

  3. Peripherally Induced Tolerance Depends on Peripheral Regulatory T Cells That Require Hopx To Inhibit Intrinsic IL-2 (show IL2 Proteins) Expression.

  4. Hopx integrates Bmp and Wnt (show WNT2 Proteins) signaling by physically interacting with activated Smads and repressing Wnt (show WNT2 Proteins) genes.

  5. Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells.

  6. HOPX/Hopx expression is reduced in multiple examples of human and murine cardiac hypertrophy and failure.

  7. Hopx regulates the expression of genes involved in regulation of apoptosis and survival and makes them refractory to Fas (show FAS Proteins)-induced apoptosis.

  8. Hopx is required for the function of regulatory T cells induced by DCs and the promotion of DC-mediated T cell unresponsiveness in vivo.

  9. Hdac2 (show HDAC2 Proteins), Hopx, and Gata4 (show GATA4 Proteins) coordinately regulate cardiac myocyte proliferation during embryonic development.

  10. data show that Hop (show STIP1 Proteins) can inhibit serum response factor-dependent transcriptional activation by recruiting histone deacetylase (HDAC (show HDAC1 Proteins)) activity and can form a complex that includes HDAC2 (show HDAC2 Proteins)

HOP Homeobox (HOPX) Protein Profile

Protein Summary

The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene.

Alternative names and synonyms associated with HOP Homeobox (HOPX)

  • HOP homeobox (HOPX)
  • homeodomain-only protein (HOP)
  • Homeodomain-only protein (hop)
  • HOP homeobox (hopx)
  • HOP homeobox (Hopx)
  • 1110018K11Rik protein
  • 1200015P04Rik protein
  • 2300002F06Rik protein
  • AI848177 protein
  • AW490897 protein
  • Cameo protein
  • GIIg15b protein
  • Hdop protein
  • Hod protein
  • Hop protein
  • HOPX protein
  • LAGY protein
  • MGC147344 protein
  • NECC1 protein
  • Ob1 protein
  • Obl protein
  • SMAP31 protein
  • Toto protein

Protein level used designations for HOP Homeobox Proteins (HOPX)

HOP homeobox , homeodomain-only protein , Homeodomain-only protein , lung cancer-associated Y protein , not expressed in choriocarcinoma clone 1 , not expressed in choriocarcinoma protein 1 , odd homeobox 1 protein , odd homeobox protein 1 , homeobox only domain , homeobox-only protein , homeodomain only protein , mOB1 , odd homeobox 1 , global ischemia induced protein GIIG15B , global ischemia-induced gene 15B protein , global ischemia-induced protein 15B

736250 Pan troglodytes
100037714 Oryctolagus cuniculus
100196138 Salmo salar
694219 Macaca mulatta
780767 Xenopus (Silurana) tropicalis
84525 Homo sapiens
74318 Mus musculus
171160 Rattus norvegicus
395241 Gallus gallus
396692 Sus scrofa
281270 Bos taurus
386589 Danio rerio
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