Browse our anti-RNA Binding Motif Protein 4 (RBM4) Antibodies

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anti-RNA Binding Motif Protein 4 Antibodies (RBM4)
On www.antibodies-online.com are 57 RNA Binding Motif Protein 4 (RBM4) Antibodies from 11 different suppliers available. Additionally we are shipping RNA Binding Motif Protein 4 Proteins (7) and many more products for this protein. A total of 68 RNA Binding Motif Protein 4 products are currently listed.
Synonyms:
4921506I22Rik, lark, Lark1, Mlark, Rbm4, Rbm4a, rna-bp4, wu:fc31f07, wu:fc57h11, ZCCHC21, ZCRB3A, zgc:56302
list all antibodies Gene Name GeneID UniProt
RBM4 5936 Q9BWF3
RBM4 19653 Q8C7Q4
RBM4 293663  

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Top referenced anti-RNA Binding Motif Protein 4 Antibodies

  1. Cow (Bovine) Polyclonal RBM4 Primary Antibody for WB - ABIN2778817 : Lin, Hsu, Tarn: Cell stress modulates the function of splicing regulatory protein RBM4 in translation control. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)

  2. Human Polyclonal RBM4 Primary Antibody for ELISA, WB - ABIN185228 : Jackson, Banfi, Guffanti, Rossi: A novel zinc finger-containing RNA-binding protein conserved from fruitflies to humans. in Genomics 1997 (PubMed)

More Antibodies against RNA Binding Motif Protein 4 Interaction Partners

Human RNA Binding Motif Protein 4 (RBM4) interaction partners

  1. RBM4 is induced and is involved in the PKM splicing switch and neuronal gene expression during hypoxia-induced neuronal differentiation.

  2. alternative splicing patterns were altered by knockdown of RBM4 in several types of neoplasms

  3. Loss of RBM4 expression is associated with colorectal cancer.

  4. The results indicate that the alanine-rich C-terminal domain, in conjunction with its conjoined RNA-binding domain(s), differentially influences the subnuclear localization and biogenesis of RBM4.

  5. Up-regulation of RBM4 is associated with breast cancer.

  6. RBM4 is a tumor suppressor with therapeutic potential and clinical values as a prognostic factor.

  7. we propose the emerging role of RBM4 in regulating the adipocyte-specific splicing events and transcription cascade, which subsequently facilitate the development and function of brown adipocyte-like cells.

  8. role in negative feed-forward loop that disrupts inflammattory cytokine translation following Toll-like receptor 4 (show TLR4 Antibodies) response

  9. RBM4 homologs exert different effects on 5' splice site utilization and exon selection, and exhibit different subnuclear localization patterns.

  10. RBM4 may synergize its effect on muscle cell-specific alternative splicing by down-regulating PTB (show PTBP1 Antibodies) expression and antagonizing the activity of PTB (show PTBP1 Antibodies) in exon selection

Mouse (Murine) RNA Binding Motif Protein 4 (RBM4) interaction partners

  1. RBM4 depletion reduced the expression of the proneural gene Mash1 (show ASCL1 Antibodies), and such reduction was reversed by an RBM4-induced Numb (show NUMB Antibodies) isoform containing exon 3 but lacking exon 9. RBM4 was also essential for neurite outgrowth from cortical neurons in vitro. Neurite outgrowth defects of RBM4-depleted neurons were rescued by RBM4-induced exon 9-lacking Numb (show NUMB Antibodies) isoforms. RBM4 modulates exon selection of Numb (show NUMB Antibodies).

  2. RBM4a ablation enhanced the relative level of exon 4-excluded neuro-oncological ventral antigen 1 (Nova1 (show NOVA1 Antibodies)(-4)) transcripts, which were predominantly generated in embryonic BAs

  3. These results constitute a mechanistic understanding of the RBM4a-modulated splicing cascade during the brown adipogenesis.

  4. The RBM4-MEF2C-miR-1 network constitutes a novel mechanism which programs the gene expression profile toward the development of brown adipocytes.

  5. RBM4 overexpression was sufficient to convert AR42J cells into insulin (show INS Antibodies)-producing cells and may mediate glucose-induced insulin (show INS Antibodies) expression and insulin receptor (show INSR Antibodies) isoform switches.

  6. RBM4 may synergize its effect on muscle cell-specific alternative splicing by down-regulating PTB (show PTBP1 Antibodies) expression and antagonizing the activity of PTB (show PTBP1 Antibodies) in exon selection

  7. LARK ia a novel posttranscriptional regulator of the mammalian circadian clock.

RNA Binding Motif Protein 4 (RBM4) Antigen Profile

Antigen Summary

RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA. Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation. Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress. Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions. Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of EIF2C2- containing miRNPs with their cognate target mRNAs. Associates with miRNAs during muscle cell differentiation. Binds preferentially to 5'-CGCGCG-3' motif in vitro (By similarity).

Alternative names and synonyms associated with RNA Binding Motif Protein 4 (RBM4)

  • RNA binding motif protein 4.1 (rbm4.1) antibody
  • RNA binding motif protein 4 (RBM4) antibody
  • RNA binding motif protein 4 (Rbm4) antibody
  • RNA-binding protein lark (LARK) antibody
  • 4921506I22Rik antibody
  • lark antibody
  • Lark1 antibody
  • Mlark antibody
  • Rbm4 antibody
  • Rbm4a antibody
  • rna-bp4 antibody
  • wu:fc31f07 antibody
  • wu:fc57h11 antibody
  • ZCCHC21 antibody
  • ZCRB3A antibody
  • zgc:56302 antibody

Protein level used designations for RBM4

RNA binding motif protein 4 , RNA-binding motif protein 4.1 , RNA-binding protein 4.1 , RNA-binding motif protein 4a , RNA-binding protein 4 , lark homolog , transcriptional coactivator CoAZ , zinc finger CCHC-type and RNA binding motif 3A , RNA-binding motif protein 4

GENE ID SPECIES
573001 Danio rerio
100611312 Pan troglodytes
5936 Homo sapiens
610648 Canis lupus familiaris
100144417 Sus scrofa
767937 Bos taurus
19653 Mus musculus
293663 Rattus norvegicus
100008755 Oryctolagus cuniculus
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