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Regulator of Calcineurin 1 ELISA Kits (RCAN1)
On www.antibodies-online.com are 8 Regulator of Calcineurin 1 (RCAN1) ELISA Kits from 5 different suppliers available. Additionally we are shipping Regulator of Calcineurin 1 Antibodies (172) and Regulator of Calcineurin 1 Proteins (16) and many more products for this protein. A total of 207 Regulator of Calcineurin 1 products are currently listed.
Synonyms:
2410048A02Rik, AA408855, Adapt78, AI429645, AL024459, AV028423, CALP1L, CDHF1, CSP1, DG2/DG3, DSC1, Dscr1, Mcip1, MGC53636, MGC69428, rcan1, RCN1, wu:fr92c05
list all ELISA KIts Gene Name GeneID UniProt
RCAN1 1823 Q08554
RCAN1 54720 Q9JHG6
RCAN1 266766 Q6IN33

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Regulator of Calcineurin 1 (RCAN1) ELISA Kits by Reactivity

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More ELISA Kits for Regulator of Calcineurin 1 Interaction Partners

Xenopus laevis Regulator of Calcineurin 1 (RCAN1) interaction partners

  1. RCAN1-regulated vascular branching which may play a role in the patterning of morphologically different vasculature.

Human Regulator of Calcineurin 1 (RCAN1) interaction partners

  1. Overexpression of RCAN1 markedly reduced glioma cells viability.

  2. RCAN1.4 prevents cell proliferation, migration, and invasion in vitro; overexpressed RCAN1.4 in HCC (show FAM126A ELISA Kits) cells prevents growth, angiogenesis, and metastases of xenograft tumors by inhibiting calcineurin activity and nuclear translocation of NFAT1 (show NFAT1 ELISA Kits).

  3. elucidated a novel function of regulator of calcineurin 1 isoform 1 in mitochondria and provides a molecular basis for the regulator of calcineurin 1 isoform over-expression-induced mitochondrial dysfunctions and neuronal apoptosis

  4. our research revealed that RCAN1 was involved in the development of small cell lung cancer, and it might be a cancer-inhibiting gene for the formation of bone metastases in small cell lung cancer

  5. The results of the study indicate that RCAN1 is suppressed in endothelial cells of chronically inflamed periodontal tissues. During an acute infection, however, rcan1 seems to be upregulated in endothelial cells, indicating a modulating role in immune homeostasis of periodontal tissues.

  6. mRNA expression levels of DSCR1 and VEGF-C (show VEGFC ELISA Kits), and microvessel density are increased in cancerous tissues, compared with paracancerous tissue in hypopharyngeal cancer.

  7. DSC1 expression is significantly downregulated in human masticatory mucosa during wound healing

  8. Increased expression of DSC1 can promote the occurrence of head and neck squamous cell carcinoma (HNSCC) and is associated with tumor. The increased expression of DSC1 also indicates a poor prognosis of the patients with HNSCC.

  9. The objective of this study was aimed to detect the association of Down syndrome critical region 1 (DSCR1) gene polymorphisms (rs149048873 and rs143081213) and congenital heart disease (CHD (show CHDH ELISA Kits)) susceptibility.

  10. Results support overexpression of RCAN1 and particularly the RCAN1.1S isoform during aging as a pathogenic mechanism in both Down syndrome-related and sporadic Alzheimer's disease

Mouse (Murine) Regulator of Calcineurin 1 (RCAN1) interaction partners

  1. The present study demonstrates that RCAN1 deficiency protects against Salmonella intestinal infection by enhancing proinflammatory JNK (show MAPK8 ELISA Kits) signaling.

  2. DSCR1 as a key protein that couples axon growth.

  3. from amongst the myriad of gene expression changes occurring in Type 2 diabetes (T2D) b-cells where we had little knowledge of which changes cause b-cell dysfunction, we applied a trisomy 21 screening approach which linked RCAN1 to b (show TDO2 ELISA Kits)-cell mitochondrial dysfunction in T2D.

  4. These results uncover a critical link between calcineurin signalling, impaired neurotrophin (show BDNF ELISA Kits) trafficking and neurodevelopmental deficits in the peripheral nervous system in Down syndrome.

  5. Data suggest that expression of Dscr1 in hippocampus can be regulated by dietary factors; supplementation of maternal diet and offspring diet with fish oil down-regulates Dscr1 in hippocampus of offspring; Dscr1 is a presumed target in Down syndrome.

  6. inhibition of the calcineurin-nuclear factor of activated T cells pathway enhances the proliferation of granulocyte-monocyte progenitors both in vitro and in vivo

  7. PACAP (show ADCYAP1 ELISA Kits) targets RCAN1 to control neuronal differentiation.

  8. We also confirmed that overexpression of RCAN1-1L could inhibit the transcriptional activation of an NFAT-dependent promoter in response to PMA and ionomycin by inhibiting Calcineurin activity in HEK293T cells

  9. found that RCAN1/3 interact with RAF (show RAF1 ELISA Kits) kinases and CN in a non-exclusive manner. Our data suggests that the balance of RCAN interactions with CN and/or RAF (show RAF1 ELISA Kits) kinases may influence T cell positive selection

  10. Calcineurin and its regulator, RCAN1, confer time-of-day changes in susceptibility of the heart to ischemia/reperfusion.

Regulator of Calcineurin 1 (RCAN1) Antigen Profile

Antigen Summary

The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.

Alternative names and synonyms associated with Regulator of Calcineurin 1 (RCAN1)

  • regulator of calcineurin 1 (RCAN1) Elisa Kit
  • regulator of calcineurin 1b (rcan1b) Elisa Kit
  • Down syndrome critical region gene 1 (dscr1) Elisa Kit
  • regulator of calcineurin 1 (rcan1) Elisa Kit
  • desmocollin 1 (DSC1) Elisa Kit
  • DSCR1-like protein (LOC443255) Elisa Kit
  • regulator of calcineurin 1 (Rcan1) Elisa Kit
  • 2410048A02Rik Elisa Kit
  • AA408855 Elisa Kit
  • Adapt78 Elisa Kit
  • AI429645 Elisa Kit
  • AL024459 Elisa Kit
  • AV028423 Elisa Kit
  • CALP1L Elisa Kit
  • CDHF1 Elisa Kit
  • CSP1 Elisa Kit
  • DG2/DG3 Elisa Kit
  • DSC1 Elisa Kit
  • Dscr1 Elisa Kit
  • Mcip1 Elisa Kit
  • MGC53636 Elisa Kit
  • MGC69428 Elisa Kit
  • rcan1 Elisa Kit
  • RCN1 Elisa Kit
  • wu:fr92c05 Elisa Kit

Protein level used designations for RCAN1

regulator of calcineurin 1 , Down syndrome critical region gene 1 , cadherin family member 1 , desmocollin-1 , desmosomal glycoprotein 2/3 , calcipressin-1 , down syndrome critical region protein 1 , Down syndrome candidate region 1 , calcium and oxidant-inducible mRNA , modulatory calcineurin-interacting protein 1 , myocyte-enriched calcineurin-interacting protein 1 , near DSCR proline-rich protein , Down syndrome critical region homolog 1 , calcineurin inhibitor , calcipressin 1 , down syndrome critical region protein 1 homolog , myocyte-enriched calcineurin interactin protein 1 , Down syndrome critical region protein 1 homolog , Oxidative-induced protein Adapt78

GENE ID SPECIES
697108 Macaca mulatta
336348 Danio rerio
380353 Xenopus laevis
448016 Xenopus (Silurana) tropicalis
1823 Homo sapiens
443255 Ovis aries
1827 Homo sapiens
54720 Mus musculus
379550 Xenopus laevis
418510 Gallus gallus
607887 Canis lupus familiaris
539640 Bos taurus
266766 Rattus norvegicus
100171642 Pongo abelii
100689474 Cricetulus griseus
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