Browse our Argininosuccinate Lyase Proteins (ASL)

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Argininosuccinate Lyase Proteins (ASL)
On are 13 Argininosuccinate Lyase (ASL) Proteins from 6 different suppliers available. Additionally we are shipping Argininosuccinate Lyase Antibodies (50) and many more products for this protein. A total of 74 Argininosuccinate Lyase products are currently listed.
2510006M18Rik, ASAL, ASL, BA4879, CRYD2, PSPTO0125, zgc:63532
list all proteins Gene Name GeneID UniProt
ASL 435 P04424
ASL 109900 Q91YI0
ASL 59085 P20673

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Argininosuccinate Lyase Proteins (ASL) by Origin

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Top referenced Argininosuccinate Lyase Proteins

  1. Human ASL Protein expressed in Escherichia coli (E. coli) - ABIN667597 : Zhao, Xu, Jiang, Yu, Lin, Zhang, Yao, Zhou, Zeng, Li, Li, Shi, An, Hancock, He, Qin, Chin, Yang, Chen, Lei, Xiong, Guan: Regulation of cellular metabolism by protein lysine acetylation. in Science (New York, N.Y.) 2010 (PubMed)
    Show all 2 references for 667597

More Proteins for Argininosuccinate Lyase Interaction Partners

Human Argininosuccinate Lyase (ASL) interaction partners

  1. Overexpression of ASL (show ADSL Proteins) may be a contributing factor in drug resistance for arginine deprivation therapy.

  2. ASL (show ADSL Proteins)-targeting shRNA-induced growth inhibition is associated with decreased cyclin A2 (show CCNA2 Proteins) expression and Nitric oxide content in colon cancer.

  3. the mechanism induced by ASL (show ADSL Proteins) shRNA which occurred in human breast cancer may be attributed to a decrease in cyclin A2 (show CCNA2 Proteins) and NO.

  4. The clinical and biochemical course in variant forms of ASL (show ADSL Proteins) deficiency is associated with relevant residual levels of ASL (show ADSL Proteins) activity as well as instability of mutant ASL (show ADSL Proteins) proteins.

  5. Point mutation of ASS1 (show ASS1 Proteins), ASL (show ADSL Proteins) and SLC25A13 (show slc25a13 Proteins) is associated with citrullinemia (show ASS1 Proteins).

  6. Data show that in patients with Argininosuccinate lyase deficiency, the ASl (show ADSL Proteins) gene is subject to several mutations, the majority are missense; some more frequent then others.

  7. Our results suggest that ASL (show ADSL Proteins) transcripts can contribute to the highly variable phenotype in ASA (show ARSA Proteins) patients if expressed at high levels.

  8. Cox (show COX8A Proteins) regression analysis showed that ASL (show ADSL Proteins) is an independent prognostic marker for HCC (show FAM126A Proteins). Therefore, reduced ASL (show ADSL Proteins) expression may be a novel maker for poor prognosis in HCC (show FAM126A Proteins) patients

  9. analysis of mutant argininosuccinate lyase in argininosuccinic aciduria

  10. extent of protection of ASL (show ADSL Proteins) and delta-crystallin at different ratios of alphaA-crystallin (show CRYAA Proteins)

Mouse (Murine) Argininosuccinate Lyase (ASL) interaction partners

  1. Enterocyte-derived ASL (show ADSL Proteins) has a protective role in necrotizing enterocolitis.

Argininosuccinate Lyase (ASL) Protein Profile

Protein Summary

This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with Argininosuccinate Lyase (ASL)

  • argininosuccinate lyase (argH-2)
  • argininosuccinate lyase (argH)
  • argininosuccinate lyase (SPBC1539.03c)
  • argininosuccinate lyase (arg7)
  • argininosuccinate lyase (CNC04420)
  • argininosuccinate lyase (STHERM_c13370)
  • argininosuccinate lyase (ASL)
  • argininosuccinate lyase (Asl)
  • argininosuccinate lyase (asl)
  • argininosuccinate lyase (ASL2)
  • 2510006M18Rik protein
  • ASAL protein
  • ASL protein
  • BA4879 protein
  • CRYD2 protein
  • PSPTO0125 protein
  • zgc:63532 protein

Protein level used designations for Argininosuccinate Lyase Proteins (ASL)

argininosuccinate lyase , argininosuccinase , arginosuccinase , ASAL , delta crystallin II , delta-2 crystallin , delta-2-crystallin

1085916 Bacillus anthracis str. Ames
1168161 Shewanella oneidensis MR-1
1181733 Pseudomonas syringae pv. tomato str. DC3000
2539950 Schizosaccharomyces pombe 972h-
2539980 Schizosaccharomyces pombe 972h-
2687872 Geobacter sulfurreducens PCA
2797120 Listeria monocytogenes serotype 4b str. F2365
3104272 Methylococcus capsulatus str. Bath
3229429 Dehalococcoides ethenogenes 195
3231520 Campylobacter jejuni RM1221
3256327 Cryptococcus neoformans var. neoformans JEC21
3726611 Carboxydothermus hydrogenoformans Z-2901
9756591 Spirochaeta thermophila DSM 6192
3196544 Ruegeria pomeroyi DSS-3
3927223 Ehrlichia chaffeensis str. Arkansas
435 Homo sapiens
109900 Mus musculus
59085 Rattus norvegicus
393423 Danio rerio
447450 Xenopus laevis
417545 Gallus gallus
479704 Canis lupus familiaris
512771 Bos taurus
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