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anti-Human Betacellulin antibody for Immunofluorescence

Recommended Betacellulin Antibody (supplied by: Log in to see )

Antigen
Betacellulin (BTC) Antibodies
  • Bcn
  • BTC
  • LOC100228121
  • probetacellulin
Epitope
AA 24-54, N-Term
9
7
6
6
5
5
2
2
1
Reactivity
Human
81
12
3
2
2
Host
Rabbit
76
10
1
1
1
Clonality
Polyclonal
Conjugate
This Betacellulin antibody is un-conjugated
12
4
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
55
37
17
11
8
5
5
5
3
2
2
2
2
1
Supplier
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Catalog No. ABIN950656
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.31611317 ABIN655615 FACS IF IHC (p) WB Rabbit Ig AA 17-45, N-Term Log in to see Polyclonal 5
0.31611317 ABIN2159612 FACS IF IHC WB Rabbit Ig Fraction N-Term Log in to see Polyclonal
0.0010850475 ABIN1806213 FACS IF IHC (p) WB Rabbit AA 24-54 Log in to see Polyclonal
0.0010850475 ABIN2210123 FACS IF IHC ELISA WB Rabbit IgG N-Term, AA 24-54 Log in to see Polyclonal
0.0010850475 ABIN2797423 FACS IF IHC WB Rabbit Ig Fraction N-Term Log in to see Polyclonal

Top referenced anti-Betacellulin antibody for Immunofluorescence

Similar anti-Betacellulin Antibodies

Application / Reactivity Human
Blocking Antibody (Inhibition) 2 Antibodies
ELISA 32 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 6 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 6 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 16 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Neutralization (Neut) 1 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Western Blotting (WB) 52 Antibodies

General

Antigen Betacellulin (BTC) Antibodies
Epitope AA 24-54, N-Term
(9), (7), (6), (6), (5), (5), (2), (2), (1)
Reactivity Human
(81), (12), (3), (2), (2)
Host Rabbit
(76), (10), (1), (1), (1)
Clonality
Polyclonal
Conjugate This Betacellulin antibody is un-conjugated
(12), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(55), (37), (17), (11), (8), (5), (5), (5), (3), (2), (2), (2), (2), (1)
Pubmed 5 references available
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Product Details anti-Betacellulin Antibody

Target Details Betacellulin Application Details Handling References for anti-Betacellulin Antibody (ABIN950656) Images
Specificity This antibody reacts to Betacellulin.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Immunogen KLH conjugated synthetic peptide between 24-54 amino acids from the N-terminal region of human BTC
Isotype Ig

Target Details Betacellulin

Product Details anti-Betacellulin Antibody Application Details Handling References for anti-Betacellulin Antibody (ABIN950656) Images back to top
Antigen
Alternative Name Betacellulin (BTC Antibody Abstract)
Background The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor.Synonyms: BTC, Probetacellulin
Molecular Weight 19746 Da
Gene ID 685
NCBI Accession NP_001720
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Betacellulin Antibody Target Details Betacellulin Handling References for anti-Betacellulin Antibody (ABIN950656) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Betacellulin Antibody Target Details Betacellulin Application Details References for anti-Betacellulin Antibody (ABIN950656) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Betacellulin Antibody (ABIN950656)

Product Details anti-Betacellulin Antibody Target Details Betacellulin Application Details Handling Images back to top
Background publications

Stoeck, Shang, Dempsey: "Sequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growth." in: Journal of cell science, Vol. 123, Issue Pt 13, pp. 2319-31, 2010

Genetos, Rao, Vidal: "Betacellulin inhibits osteogenic differentiation and stimulates proliferation through HIF-1alpha." in: Cell and tissue research, Vol. 340, Issue 1, pp. 81-9, 2010

Nagaoka, Fukuda, Hashizume, Nishiyama, Tada, Yamada, Salomon, Yamada, Kojima, Seno: "A betacellulin mutant promotes differentiation of pancreatic acinar AR42J cells into insulin-producing cells with low affinity of binding to ErbB1." in: Journal of molecular biology, Vol. 380, Issue 1, pp. 83-94, 2008

Révillion, Lhotellier, Hornez, Bonneterre, Peyrat: "ErbB/HER ligands in human breast cancer, and relationships with their receptors, the bio-pathological features and prognosis." in: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, Vol. 19, Issue 1, pp. 73-80, 2007

Moss, Bomar, Liu, Sage, Dempsey, Lenhart, Gillispie, Stoeck, Wildeboer, Bartsch, Palmisano, Zhou: "The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events." in: The Journal of biological chemistry, Vol. 282, Issue 49, pp. 35712-21, 2007

Images

Product Details anti-Betacellulin Antibody Target Details Betacellulin Application Details Handling References for anti-Betacellulin Antibody (ABIN950656) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Betacellulin antibody (BTC) (AA 24-54) (ABIN950656) BTC Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compar...
Immunofluorescence (IF) image for anti-Betacellulin antibody (BTC) (AA 24-54) (ABIN950656) Confocal immunofluorescent analysis of BTC Antibody (N-term)(Cat#AP50402PU-N) with MD...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Betacellulin antibody (BTC) (AA 24-54) (ABIN950656) BTC Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin em...
Western Blotting (WB) image for anti-Betacellulin antibody (BTC) (AA 24-54) (ABIN950656) BTC Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35µg/lane...