anti-Rat (Rattus) FGFR4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FGFR4 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
  • FGFR4
  • XFGFR-4
  • XFGFR-4a
  • cd334
  • fgfr-4
  • jtk2
  • tkf
  • xfgfr4
  • CD334
  • JTK2
  • TKF
  • Fgfr-4
  • etID309818.21
  • wu:fc13h10
  • zgc:111935
  • fgfr-4c
  • fgfr4
  • fibroblast growth factor receptor 4
  • FGFR4
  • fgfr4
  • Fgfr4
  • fgfr4-b
Epitope
AA 1-367
18
16
13
10
9
8
7
6
6
4
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Rat (Rattus)
189
54
44
3
3
Host
Rabbit
121
64
17
1
Clonality
Polyclonal
Conjugate
This FGFR4 antibody is un-conjugated
8
7
7
4
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
146
92
53
51
28
26
13
9
8
5
4
3
2
1
1
Supplier
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Catalog No. ABIN2001665
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN671766 FACS IF (p) IHC (p) WB Rabbit IgG AA 40-90 Log in to see Polyclonal
1 ABIN671775 IHC (p) WB HRP Rabbit IgG AA 40-90 Log in to see Polyclonal
1 ABIN671768 IHC (p) WB Biotin Rabbit IgG AA 40-90 Log in to see Polyclonal

Similar anti-FGFR4 Antibodies

Application / Reactivity Rat (Rattus)
Cell Culture (CC) 1 Antibodies
ELISA 17 Antibodies
Flow Cytometry (FACS) 14 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Western Blotting (WB) 28 Antibodies

General

Antigen Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
Epitope AA 1-367
(18), (16), (13), (10), (9), (8), (7), (6), (6), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Rat (Rattus)
(189), (54), (44), (3), (3)
Host Rabbit
(121), (64), (17), (1)
Clonality
Polyclonal
Conjugate This FGFR4 antibody is un-conjugated
(8), (7), (7), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(146), (92), (53), (51), (28), (26), (13), (9), (8), (5), (4), (3), (2), (1), (1)
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Product Details anti-FGFR4 Antibody

Target Details FGFR4 Application Details Handling Images
Specificity Rat FGFR4 / FGF Receptor 4
Characteristics Produced in rabbits immunized with purified, recombinant Rat FGFR4 / FGF Receptor 4 (rR FGFR4 / FGF Receptor 4, ABIN2009148 Q498D6, Met1-Asp367,. FGFR4 / FGF Receptor 4 specific IgG was purified by Rat FGFR4 / FGF Receptor 4 affinity chromatography.
Purification purified by affinity chromatography
Sterility 0.2 μm filtered
Immunogen Recombinant Rat FGFR4 / FGF Receptor 4 protein (ABIN2009148)
Isotype IgG

Target Details FGFR4

Product Details anti-FGFR4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name FGFR4 (FGFR4 Antibody Abstract)
Background FGFR4, also designated as CD334, is a member of the fibroblast growth factor receptor subfamily which belongs to the tyrosine protein kinase superfamily. Upon ligand binding, FGFRs undergo dimerization and autophosphorylation, intiating a cascade of downstream signal pathways, ultimately influencing a variety of physiological and pathological cellular processes including mitogenesis and differentiation. FGFR members is highly conserved in amino acid sequence and differ in their ligand affinities and tissue distribution. FGFR4, a type I transmembrane glycoprotein, contains 3 immunoglobulin-like domains in the extracellular domain and a cytoplasmic tyrosine-kinase domain. FGFR4 expression is detected in gastrointestinal epithelial cells, pancreas, as well as gastric and pancreatic cancer cell lines. FGFR4 is reported to be a high affinity receptor for both acidic and basic fibroblast growth factor, and also binds to FGF19. Like FGFR1-3, several isoforms of FGFR4 are generated by alternative splicing of the mRNAs. Although its specific function is unknown, growing studies have indicated that FGFR4 plays a role in tumorigenesis and malignace of cetain carcinomas such as breast and ovarian tumors.
UniProt Q498D6
Research Area Cancer, Growth Factors, Angiogenesis, Receptors
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding

Application Details

Product Details anti-FGFR4 Antibody Target Details FGFR4 Handling Images back to top
Application Notes ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Rat FGFR4 / FGF Receptor 4. The detection limit for Rat FGFR4 / FGF Receptor 4 is approximately 0.00245 ng/well.
IHC-P: 0.1-1 μg/mL
Restrictions For Research Use only

Handling

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months

Images

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-FGFR4 antibody (Fibroblast Growth Factor Receptor 4) (AA 1-367) (ABIN2001665) Immunochemical staining of rat FGFR4 in rat intestine with rabbit polyclonal antibody...