Browse our F-Box Protein 11 Proteins (FBXO11)

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F-Box Protein 11 Proteins (FBXO11)
On are 9 F-Box Protein 11 (FBXO11) Proteins from 3 different suppliers available. Additionally we are shipping F-Box Protein 11 Antibodies (80) and F-Box Protein 11 Kits (12) and many more products for this protein. A total of 107 F-Box Protein 11 products are currently listed.
C80048, DKFZp459P2410, FBX11, Fbxo11, im:6906507, Jf, MGC84634, PRMT9, UBR6, Vit1, wu:fj83f06, zgc:153171
list all proteins Gene Name GeneID UniProt
FBXO11 80204 Q86XK2
FBXO11 225055  
Rat FBXO11 FBXO11 301674 Q7TSL3

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F-Box Protein 11 Proteins (FBXO11) by Origin

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More Proteins for F-Box Protein 11 Interaction Partners

Human F-Box Protein 11 (FBXO11) interaction partners

  1. FBXO11 is a direct target of miR (show MLXIP Proteins)-621 in breast cancer cells.

  2. UBR3/6 regulate cardiomyocyte Nav 1.5 channel protein levels via the ubiquitin-proteasome pathway.

  3. siRNA-mediated knockdown of FBXO11 facilitated HIF-1alpha (show HIF1A Proteins) expression in various cancer cells and HIF-1alpha (show HIF1A Proteins)-driven gene expressions, but the FBXO10 (show FBXO10 Proteins) knockdown did not.

  4. Our results identify FBXO11 as a novel miR (show MLXIP Proteins)-21 target gene, and demonstrate that the oncogenic miRNA miR (show MLXIP Proteins)-21 decreases the expression of FBXO11, which normally acts as a tumor suppressor, and thereby promotes tumorigenesis.

  5. study defined eight additional recurrently mutated genes in SMZL; these genes are CREBBP, CBFA2T3, AMOTL1, FAT4, FBXO11, PLA2G4D, TRRAP and USH2A.

  6. The PKD1 (show PKD1 Proteins)-FBXO11-SNAIL (show SNAI1 Proteins) axis is a mechanism of posttranslational regulation of epithelial-mesenchymal transition and cancer metastasis.

  7. TGF-beta signaling promotes exit from the cell cycle and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2.

  8. The functional interaction between FBXO11 and CDT2 is evolutionary conserved from worms to humans and plays an important role in regulating the timing of cell-cycle exit.

  9. Migration of epithelial cells is stimulated by CRL1 (show IL27RA Proteins)(FBXO11)-mediated downregulation of Cdt2 (show DTL Proteins) and the consequent stabilization of Set8 (show SETD8 Proteins).

  10. A molecular mechanism controlling BCL6 (show BCL6 Proteins) stability--mutations and deletions in FBXO11 contribute to lymphomagenesis through BCL6 (show BCL6 Proteins) stabilization

Mouse (Murine) F-Box Protein 11 (FBXO11) interaction partners

  1. FBXO11 inactivation was associated with the development of lymphoproliferative disorders in mice.

  2. FBXO11 regulates the TGF-beta (show TGFB1 Proteins) pathway in the embryonic lung via cross-talk with p53 (show TP53 Proteins).

  3. FBXO11 is one of the first molecules to be identified, contributing to the genetic aetiology of otitis media

  4. Relationship between dilation of endoplasmic reticulum and decreased levels of the FBXO11 gene in vitiligo (show MITF Proteins) melanocytes.

F-Box Protein 11 (FBXO11) Protein Profile

Protein Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It can function as an arginine methyltransferase that symmetrically dimethylates arginine residues, and it acts as an adaptor protein to mediate the neddylation of p53, which leads to the suppression of p53 function. This gene is known to be down-regulated in melanocytes from patients with vitiligo, a skin disorder that results in depigmentation. Polymorphisms in this gene are associated with chronic otitis media with effusion and recurrent otitis media (COME/ROM), a hearing loss disorder, and the knockout of the homologous mouse gene results in the deaf mouse mutant Jeff (Jf), a single gene model of otitis media. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with F-Box Protein 11 (FBXO11)

  • F-box protein 11 (FBXO11)
  • F-box protein 11a (fbxo11a)
  • F-box protein 11 (fbxo11)
  • F-box only protein 11 (CpipJ_CPIJ009919)
  • F-box only protein 11 (CpipJ_CPIJ017549)
  • F-box only protein 11 (Bm1_52225)
  • F-box only protein 11 (LOAG_02072)
  • F-box protein 11 (Fbxo11)
  • F-box only protein 11 (LOC100351392)
  • C80048 protein
  • DKFZp459P2410 protein
  • FBX11 protein
  • Fbxo11 protein
  • im:6906507 protein
  • Jf protein
  • MGC84634 protein
  • PRMT9 protein
  • UBR6 protein
  • Vit1 protein
  • wu:fj83f06 protein
  • zgc:153171 protein

Protein level used designations for F-Box Protein 11 Proteins (FBXO11)

F-box only protein 11 , F-box protein 11 , fj83f06 , F-box only protein 11-like , f-box only protein 11-like , protein arginine N-methyltransferase 9 , ubiquitin protein ligase E3 component n-recognin 6 , vitiligo-associated protein 1 , vitiligo-associated protein VIT-1 , GENA 104 , jeff

508172 Bos taurus
777607 Danio rerio
421289 Gallus gallus
100624629 Sus scrofa
446439 Xenopus laevis
459219 Pan troglodytes
481363 Canis lupus familiaris
6042345 Culex quinquefasciatus
6051322 Culex quinquefasciatus
6105329 Brugia malayi
9939454 Loa loa
100036658 Xenopus (Silurana) tropicalis
100115478 Nasonia vitripennis
100174158 Pongo abelii
100414214 Callithrix jacchus
100472231 Ailuropoda melanoleuca
100541804 Meleagris gallopavo
100562601 Anolis carolinensis
100581026 Nomascus leucogenys
100351392 Oryctolagus cuniculus
80204 Homo sapiens
225055 Mus musculus
301674 Rattus norvegicus
101107682 Ovis aries
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