Browse our POU4F3 Proteins (POU4F3)

Full name:
POU Domain, Class 4, Transcription Factor 3 Proteins (POU4F3)
On www.antibodies-online.com are 5 POU Domain, Class 4, Transcription Factor 3 (POU4F3) Proteins from 3 different suppliers available. Additionally we are shipping POU4F3 Antibodies (62) and many more products for this protein. A total of 77 POU4F3 products are currently listed.
Synonyms:
BRN-3, BRN-3.1, brn-3c, BRN3, Brn3.1, Brn3c, ddl, DFNA15, dreidel, POU4F3
list all proteins Gene Name GeneID UniProt
POU4F3 5459 Q15319
Rat POU4F3 POU4F3 364855  
POU4F3 18998 Q63955

Show all synonyms

POU4F3 Proteins (POU4F3) by Origin

Select your origin of interest

More Proteins for POU4F3 Interaction Partners

Human POU Domain, Class 4, Transcription Factor 3 (POU4F3) interaction partners

  1. DFNA52 were mapped between STR (show STATH Proteins) D5S2056 and D5S638 on chromosome, and analysis candidate genes in this region did not reveal any potentially pathogenic mutations segregating with congenital sensorineural hearing loss.

  2. Mutations in POU4F3 are a relatively common cause of autosomal dominant nonsyndromic hearing loss in Chinese Hans.

  3. Novel 12 POU4F3 likely pathogenic variants (six missense variants, three frameshift variants, and three nonsense variants) were successfully identified in 15 probands (2.5%) among 602 families exhibiting autosomal dominant hearing loss, whereas no variants were detected in the other 1,947 probands with autosomal recessive or inheritance pattern unknown hearing loss.

  4. results indicated GRHL2 (show GRHL2 Proteins) might be a noise-induced hearing loss (NIHL) susceptibility gene, but the effect of POU4F3 on NIHL could only be detected when taking noise exposure into account and their effects were enhanced by higher levels of noise exposure

  5. this study identified a novel heterozygous mutation (c.602delT, p.L201fs) in the gene POU4F3 within a large hearing impaired Chinese family.

  6. This study showed that Mendelian sensorineural hearing loss exhibits vestibular dysfunction, including DFNA9 (show COCH Proteins), DFNA11, DFNA15 and DFNA28 (show GRHL2 Proteins).

  7. The pou4f3 gene is regulated by ATOH1 (show ATOH1 Proteins) and other transcription factors in cochlear hair cells.

  8. These data demonstrate that Nr2f2 (show NR2F1 Proteins) is a direct target of POU4F3 in vitro and that this regulatory relationship may be relevant to hair cell development and survival.

  9. new variants in genes such as POU4F3 is associated with nonsyndromic deafness and vestibular dysfunction

  10. SNP linkage analysis and whole exome sequencing identify a novel POU4F3 mutation in autosomal dominant late-onset nonsyndromic hearing loss (DFNA15).

Mouse (Murine) POU Domain, Class 4, Transcription Factor 3 (POU4F3) interaction partners

  1. These data illuminate a genetic pathway that initiates auditory HC regeneration and suggest p27(Kip1 (show CDKN1B Proteins)), GATA3 (show GATA3 Proteins), and POU4F3 as additional therapeutic targets for ATOH1 (show ATOH1 Proteins)-mediated auditory hair cells regeneration.

  2. These data demonstrate that Nr2f2 (show NR2F2 Proteins) is a direct target of POU4F3 in vitro and that this regulatory relationship may be relevant to hair cell development and survival.

  3. Data indicate that Brn3 (show POU4F1 Proteins) transcription factors Brn3b (show POU4F2 Proteins) affects Brn3a (show POU4F1 Proteins) and Brn3c positive Retinal Ganglion Cells (RGCs) in cell autonomous and non-cell autonomous fashion.

  4. induction of POU4F3 by TFE2 and GATA3 (show GATA3 Proteins)

  5. neither Brn3a (show POU4F1 Proteins) nor Brn3c are expressed in intrinsically photosensitive retinal ganglion cells

  6. Data show that Ap-2delta occupies and activates the Pou4f3 and Bhlhb4 (show BHLHE23 Proteins) promoters.

  7. Stress-granule-associated protein Caprin-1 is downregulated by Pou4f3.

  8. Taken together, our data suggest that SHH (show SHH Proteins) plays an important role in the promotion of auditory hair cell differentiation via the Math1 (show ATOH1 Proteins)-Brn3.1 signaling pathway.

  9. Brn3c null mice show severe compromised production of these neurotrophins and should therefore show a comparable pattern of nerve fiber loss.

  10. Brn-3c was found to contain an independent N-terminal activation domain that is sufficient to activate gene transcription in the organ-of-Corti-derived cell lines.

POU4F3 Protein Profile

Protein Summary

This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15.

Alternative names and synonyms associated with POU4F3

  • POU class 4 homeobox 3 (POU4F3)
  • POU class 4 homeobox 3 (Pou4f3)
  • POU domain, class 4, transcription factor 3 (pou4f3)
  • POU domain, class 4, transcription factor 3 (Pou4f3)
  • BRN-3 protein
  • BRN-3.1 protein
  • brn-3c protein
  • BRN3 protein
  • Brn3.1 protein
  • Brn3c protein
  • ddl protein
  • DFNA15 protein
  • dreidel protein
  • POU4F3 protein

Protein level used designations for POU4F3

POU class 4 homeobox 3 , POU domain, class 4, transcription factor 3 , brain-3 , brain-specific homeobox/POU domain protein 3 , brain-3C , brain-specific homeobox/POU domain protein 3C , brn-3C , brain POU domain gene 3.1 , brain-3.1 , brain-specific homeobox/POU domain protein 3.1 , zfbrn-3.1 , brain-specific homeobox POU domain protein 3C

GENE ID SPECIES
471685 Pan troglodytes
395521 Gallus gallus
5459 Homo sapiens
487200 Canis lupus familiaris
100510953 Sus scrofa
538520 Bos taurus
364855 Rattus norvegicus
30534 Danio rerio
18998 Mus musculus
Selected quality suppliers for POU4F3 Proteins (POU4F3)
Did you look for something else?