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Human NRP2 ELISA Kit for Sandwich ELISA - ABIN415192
Scheerer, Frangini, Chiantera, Mechsner: Reduced Sympathetic Innervation in Endometriosis is Associated to Semaphorin 3C and 3F Expression. in Molecular neurobiology 2016
Study identifies NRP2 (show NELL2 ELISA Kits) and ESL-1 (show GLG1 ELISA Kits) as targets for polysialylation in murine microglia and human THP-1 (show GLI2 ELISA Kits) macrophages and reveals a striking convergence in the regulation of the two polysialylated acceptors in the course of inflammatory activation. A pool of polysialylated NRP2 (show NELL2 ELISA Kits) and ESL-1 (show GLG1 ELISA Kits) is assembled after injury or in culture and its shedding is an early response to lipopolysaccharide-induced activation of microglia.
Neuropilin 2 isoform NRP2b contributed to the oncogenic response to transforming growth factor-beta (TGFbeta (show TGFB1 ELISA Kits)) and correlated with tumor progression in non-small cell lung cancer (NSCLC) patients.
Sema3a (show SEMA3A ELISA Kits)-Nrp2 (show NELL2 ELISA Kits) signaling along an unrecognized pancreatic developmental axis constitutes a chemoattractant system essential for generating the hallmark morphogenetic properties of pancreatic islets.
NRP2 (show NELL2 ELISA Kits) promotes tumourigenesis and metastasis in Oesophageal squamous cell carcinoma (ESCC) through deregulation of ERK-MAPK (show MAPK1 ELISA Kits)-ETV4 (show ETV4 ELISA Kits)-MMP-E-cadherin (show CDH1 ELISA Kits) signalling.
The summarizes the structure and function features of pathway-related molecules of VEGFC (show VEGFC ELISA Kits)/D-VEGFR3 (show FLT4 ELISA Kits)/NRP2 (show NELL2 ELISA Kits) axis, stages of various tumors and their molecular mechanisms and significances in tuthe expression changes of these molecules in different anatomic organs or histopathologic types or development lymphatic metastasis.
NRP2 inhibits WDFY1 transcription by preventing the nuclear localization of a transcription factor, Fetal ALZ50-reactive clone 1 (FAC1).
Sequence Requirements for Neuropilin-2 Recognition by ST8SiaIV (show ST8SIA4 ELISA Kits) and Polysialylation of Its O-Glycans.
the concurrent high expression of VEGF-C (show VEGFC ELISA Kits) and NRP2 (show NELL2 ELISA Kits) is predictive of the unfavorable prognosis in glioblastoma.
SEMA3F (show SEMA3F ELISA Kits)-NRP2 (show NELL2 ELISA Kits) interactions inhibit intracellular PI-3K activity, mTORC2 (show CRTC2 ELISA Kits)-dependent signaling, RhoA (show RHOA ELISA Kits) activity and cytoskeletal stress fiber formation.
NRP2 (show NELL2 ELISA Kits)/WDFY1 (show WDFY1 ELISA Kits) axis is required for maintaining endocytic activity in cancer cells, which supports their oncogenic activities and confers drug resistance.
Study identifies NRP2 and ESL-1 (show GLG1 ELISA Kits) as targets for polysialylation in murine microglia and human THP-1 (show GLI2 ELISA Kits) macrophages and reveals a striking convergence in the regulation of the two polysialylated acceptors in the course of inflammatory activation. A pool of polysialylated NRP2 and ESL-1 (show GLG1 ELISA Kits) is assembled after injury or in culture and its shedding is an early response to lipopolysaccharide-induced activation of microglia.
Sema3F (show SEMA3F ELISA Kits)-Npn-2/PlexA3 (show PLXNA3 ELISA Kits) signaling is essential for cell surface AMPAR homeostatic downscaling in response to an increase in neuronal activity, Npn-2 associates with AMPA (show GRIA3 ELISA Kits)-type glutamate (show GRIN1 ELISA Kits) receptors
Sema3G (show SEMA3G ELISA Kits) induces cell collapse in an Nrp2/PlexinD1-dependent manner.
Sema3a (show SEMA3A ELISA Kits)-Nrp2 signaling along an unrecognized pancreatic developmental axis constitutes a chemoattractant system essential for generating the hallmark morphogenetic properties of pancreatic islets.
Nrp2 deficiency increased blood vessel permeability and decreased lymphatic vessel drainage during inflammation, highlighting the importance of the NRP2/SEMA3F (show SEMA3F ELISA Kits) pathway in the modulation of tissue swelling and resolution of postinflammatory edema.
These results point to a new role for NRP2 in the positioning of neurons during adult hippocampal neurogenesis, acting via the GSK3beta (show GSK3b ELISA Kits) signaling pathway.
The authors demonstrate that expression of Semaphorin-3F (show SEMA3F ELISA Kits) in the outer hair cell region inhibits type I spiral ganglion neuron process extension by activating Neuropilin-2 receptors expressed on spiral ganglion neurons.
neuropilin-2 is developmentally regulated.
Data show that Chicken ovalbumin upstream promoter transcription factor (show NR2F1 ELISA Kits) II (COUP-TFII (show NR2F2 ELISA Kits))-induced expression of Neuropilin-2 (Nrp2) and its down-regulation control the destination of preoptic area (POa)-derived GABAergic neurons.
Study demonstrates that polysialic acid-SynCAM 1 (show CADM1 ELISA Kits) defines a subpopulation of NG2 (show Vcan ELISA Kits) cells and identifies the presence of polysialic acid-NRP2 in microglia
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C and SEMA3F protein sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
, receptor for VEGF165 and semaphorins class3
, vascular endothelial cell growth factor 165 receptor 2