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Browse our Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Proteins (CHRNA1)

Full name:
Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Proteins (CHRNA1)
On www.antibodies-online.com are 18 Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1) Proteins from 5 different suppliers available. Additionally we are shipping Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Antibodies (89) and Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Kits (21) and many more products for this protein. A total of 136 Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) products are currently listed.
Synonyms:
Achr-1, ACHRA, ACHRD, Acra, AI385656, AI608266, CHRNA, CHRNA1, CMS2A, FCCMS, NACHRA1, SCCMS
list all proteins Gene Name GeneID UniProt
CHRNA1 1134 P02708
Rat CHRNA1 CHRNA1 79557 P25108
CHRNA1 11435 P04756

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Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Proteins (CHRNA1) by Origin

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More Proteins for Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) Interaction Partners

Human Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1) interaction partners

  1. Study indicated that nicotinic acetylcholine receptor alpha 1-subunit peptides may act as receptor decoy molecules and inhibit the binding of virus to the native host cell receptors and hence may reduce viral infection.

  2. ChRnA1 gene variants did not affect the pharmacodynamics of rocuronium.

  3. Cholesterol and CAV-1 (show CAV1 Proteins) modulate the function and dynamics of the slow channel congenital myasthenia syndrome alphaC418W nicotinic acetylcholine receptor mutation.

  4. nicotine contributes to the progression and erlotinib-resistance of the NSCLC xenograft model via the cooperation between nAChR (show CHRNA4 Proteins) and EGFR (show EGFR Proteins).

  5. show that AON complementary to the 5' splice site of the exon was the most effective at exon skipping of the minigene with causative mutations, as well as endogenous wild-type CHRNA1

  6. The CHRNA1 extracellular domain is an improved protein for use in antigen-specific Myasthenia Gravis therapeutic strategies.

  7. HnRNP L (show HNRNPL Proteins) and hnRNP (show HNRNPC Proteins) LL antagonistically modulate PTB (show PTBP1 Proteins)-mediated splicing suppression of CHRNA1 pre-mRNA.

  8. High expression of CHRNA1 is associated with lung adenocarcinoma after complete resection.

  9. No mutations were found in CHRNG (show CHRNG Proteins), CHRND (show CHRND Proteins) and CHRNA1 genes of Indian families with Escobar syndrome.

  10. Findings identify a novel lung cancer risk locus on 2q31.1 which correlates with CHRNA1 expression and replicate previous associations on 15q25.1 in African-Americans.

Mouse (Murine) Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1) interaction partners

  1. This study demonstrates that genes coding for CHRNA1 subunits may contain variants associated with statin-induced ADRs.

  2. Chrna1 was co-purified with nicotinic acetylcholine receptor (AChR) in C2C12 myotubes. In addition, Stau1 (show STAU1 Proteins) was found to interact with Chrna1 mRNA, and knocking down of Stau1 (show STAU1 Proteins) by RNAi resulted in defective AChR clustering.

  3. These results suggest that in skeletal muscle cells, neural activity reduces the molar ratio of YB-1 (show YBX1 Proteins) relative to its binding AChR alpha mRNA, leading to an increase of ribosome binding to the mRNA, and thus activating translation.

  4. Chrna1 could be the first transcriptional target of atonal homolog 1 in the inner ear

  5. These data identify caveolin-3 (show CAV3 Proteins) as a critical component of the signaling machinery that drives nicotinic acetylcholine receptor clustering and controls neuromuscular junction function.

  6. HDAC4 (show HDAC5 Proteins) is a neural activity-regulated deacetylase and a key signaling component that relays neural activity to the muscle transcriptional machinery through Dach2 (show DACH2 Proteins), myogenin (show MYOG Proteins), and nAChR (show CHRNA4 Proteins)

  7. In S269I, mutant the peak-current amplitude decreases along trains of nearly saturating ACh (show FGFR3 Proteins) pulses delivered at physiologically relevant frequencies, consistent with enhanced entry into desensitization in congenital myasthenic syndrome.

  8. In this mouse experiemntal myasthenia gravis study demonstrated that Acetylcholine receptor-alpha1 subunit expression was increase with varying disease severity.

Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1) Protein Profile

Protein Summary

The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with Cholinergic Receptor, Nicotinic, alpha 1 (Muscle) (CHRNA1)

  • acetylcholine receptor alpha subunit (ACHR)
  • cholinergic receptor, nicotinic, alpha 1 (muscle) (CHRNA1)
  • cholinergic receptor, nicotinic, alpha 1 (muscle) (Chrna1)
  • cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) (Chrna1)
  • Achr-1 protein
  • ACHRA protein
  • ACHRD protein
  • Acra protein
  • AI385656 protein
  • AI608266 protein
  • CHRNA protein
  • CHRNA1 protein
  • CMS2A protein
  • FCCMS protein
  • NACHRA1 protein
  • SCCMS protein

Protein level used designations for CHRNA1

acetylcholine receptor subunit alpha , acetylcholine receptor, nicotinic, alpha 1 (muscle) , cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) , muscle nicotinic acetylcholine receptor , nicotinic acetylcholine receptor alpha subunit , nicotinic cholinergic receptor alpha 1 , muscle nicotinic acetylcholine receptor alpha-su exon P4 , nachr alpha-subunit , nicotinic acetylcholine recepter alpha-subunit , cholinergic receptor nicotinic alpha polypeptide 1 , alpha-1 subunit, nicotinic acetylcholine receptor , nicotinic cholinergic receptor alpha polypeptide 1

GENE ID SPECIES
751106 Felis catus
1134 Homo sapiens
403757 Canis lupus familiaris
338070 Bos taurus
79557 Rattus norvegicus
395608 Gallus gallus
396587 Sus scrofa
101110120 Ovis aries
11435 Mus musculus
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