Browse our anti-UGT1A4 (UGT1A4) Antibodies

Full name:
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A4 Antibodies (UGT1A4)
On are 11 UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4) Antibodies from 7 different suppliers available. Additionally we are shipping UGT1A4 Proteins (3) and many more products for this protein. A total of 17 UGT1A4 products are currently listed.
list all antibodies Gene Name GeneID UniProt
UGT1A4 54657 P22310

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anti-Human UGT1A4 Antibodies:

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Top referenced anti-UGT1A4 Antibodies

  1. Human Polyclonal UGT1A4 Primary Antibody for WB - ABIN2782758 : Kaku, Ogura, Nishiyama, Ohnuma, Muro, Hiratsuka: Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4. in Biochemical pharmacology 2004 (PubMed)

More Antibodies against UGT1A4 Interaction Partners

Human UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4) interaction partners

  1. This study aimed to analyze the relationship of UGT2B7 (show UGT2B7 Antibodies) and UGT1A4 polymorphisms with metabolism of valproic acid (VPA) and lamotrigine (LTG (show TNFSF14 Antibodies)) in epileptic children. UGT1A4 L48V polymorphism was not related with the serum concentration of LTG (show TNFSF14 Antibodies) (F=5.328, P=0.006). L48V polymorphism also showed effects on efficacy of LTG (show TNFSF14 Antibodies) (chi2=17.397, P=0.001).

  2. No association between non-bullous skin reactions from lamotrigine and heterozygosity of UGT1A4 genetic variants *2(P24T) or *3(L48V) in Norwegian patients.

  3. The frequencies of two common UGT1A4 variants, *2 (P24T) and *3 (L48V), and their potential effects on serum concentrations of LTG (show TNFSF14 Antibodies).

  4. Influence of valproic acid concentration and polymorphism of UGT1A4*3, UGT2B7 (show UGT2B7 Antibodies) -161C > T and UGT2B7 (show UGT2B7 Antibodies)*2 on serum concentration of lamotrigine in Chinese epileptic children

  5. This descriptive study examines correlations between concentrations of tamoxifen's glucuronide metabolites and genotypes UGT1A4, UGT2B7 (show UGT2B7 Antibodies), UGT2B15 (show UGT2B15 Antibodies) and UGT2B17 in 132 patients with estrogen receptor (show ESR1 Antibodies)-positive breast cancer under treatment with tamoxifen

  6. in tumor liver microsomes from HCC (show FAM126A Antibodies) patients, either V(max) (maximum reaction rate, R(max) for UGT1A1 (show UGT1A1 Antibodies)) or clearance rates (V(max)/K(m), Clint (show CLINT1 Antibodies)) of UGT1A (show UGT1A1 Antibodies), UGT1A1 (show UGT1A1 Antibodies), UGT1A4, UGT1A9 (show UGT1A9 Antibodies) and UGT2B7 (show UGT2B7 Antibodies) were lower than those in the adjacent normal liver microsomes

  7. The association between the UGT1A4 promoter and coding region SNPs and the glucuronidation rates of Tam (show CCNA1 Antibodies).

  8. Correlation of the UGT1A4 gene polymorphism with serum concentration and therapeutic efficacy of lamotrigine in Han Chinese of Northern China

  9. Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3.

  10. the substrate specificity of UGT2B10, highlighting its preference for tertiary amines with higher affinities and clearance values than those of UGT1A4 and UGT1A3.

UGT1A4 Antigen Profile

Antigen Summary

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.

Alternative names and synonyms associated with UGT1A4

  • UDP glucuronosyltransferase 1 family, polypeptide A4 (UGT1A4) antibody
  • UDP-glucuronosyltransferase 1-4 (UGT1-4) antibody
  • HUG-BR2 antibody
  • UDPGT antibody
  • UDPGT 1-4 antibody
  • UGT-1D antibody
  • UGT1 antibody
  • UGT1-04 antibody
  • UGT1.4 antibody
  • UGT1A4 antibody
  • UGT1D antibody

Protein level used designations for UGT1A4

UDP glycosyltransferase 1 family, polypeptide A4 , UDP-glucuronosyltransferase 1-4 , UDP-glucuronosyltransferase 1-D , UDP-glucuronosyltransferase 1A4 , bilirubin UDP-glucuronosyltransferase isozyme 2 , bilirubin-specific UDPGT isozyme 2

54657 Homo sapiens
100038310 Oryctolagus cuniculus
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