Phone:: +1 877 302 8632
Fax:: +1 888 205 9894 (Toll-free)
E-Mail:: orders@antibodies-online.com

For best experience we recommend to activate Javascript in your browser.

SNCA Proteins

(Synuclein, alpha (SNCA))

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].

Recommended next Filters:

All filter options

Would you like to try our new AI Search?

53 results

SNCA Protein (A53T)

SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active

Primary rat hippocampal neurons show lewy body inclusion formation when treated with A53T mutant Alpha Synuclein Protein Pre-formed Fibrils (ABIN6952303, ABIN6952304 and ABIN6952305) (B) but not when treated with a media control (A).

Evaluation of a-syn toxicity on primary mouse cortical neurons.

TEM of A53T alpha synuclein Pre-formed Fibrils (ABIN6952303, ABIN6952304 and ABIN6952305)

TEM of A53T alpha synuclein Pre-formed Fibrils (ABIN6952303, ABIN6952304 and ABIN6952305)

Thioflavin T is a fluorescent dye that binds to beta sheet-rich structures such as those in alpha synuclein fibrils.

Evaluation of a-syn toxicity on primary mouse cortical neurons.

6 images

Catalog No. ABIN6952303

SNCA Protein (full length)

SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active

SDS-PAGE of ~14 kDa Type 1 Mouse Recombinant Alpha Synuclein Protein Pre-formed Fibrils (ABIN5651245, ABIN5651246 and ABIN5651247).

TEM of Type 1 mouse alpha synuclein Pre-formed Fibrils (ABIN5651245, ABIN5651246 and ABIN5651247).

Primary rat hippocampal neurons show lewy body inclusion formation and loss of cells when treated with Type 1 mouse Alpha Synuclein Protein Pre-formed Fibrils (ABIN5651245, ABIN5651246 and ABIN5651247) at 4 μg/mL (D-F) on DVI2, but not when treated with a control (A-C).

C57/BL6 mice were injected with sonicated recombinant mouse alpha synuclein monomers or fibrils at 8 weeks of age.

C57/BL6 mice were injected with 5 μg sonicated mouse recombinant alpha synuclein PFFs (ABIN5651245, ABIN5651246 and ABIN5651247) at 8 weeks of age.

Immunohistochemistry analysis of rat brain injected with Type 1 mouse alpha synuclein PFFs (ABIN5651245, ABIN5651246 and ABIN5651247).

Primary mouse hippocampal neurons treated with 100 nM sonicated mouse alpha synuclein PFFs (ABIN5651245, ABIN5651246 and ABIN5651247) (A).

TEM of Type 1 mouse alpha synuclein Pre-formed Fibrils (ABIN5651245, ABIN5651246 and ABIN5651247).

Type 1 alpha synuclein Pre-formed Fibrils (ABIN5651245, ABIN5651246 and ABIN5651247) seed the formation of new alpha synuclein fibrils from the pool of alpha synuclein monomers (ABIN5651245, ABIN5651246 and ABIN5651247).

9 images

Catalog No. ABIN5651245

SNCA Protein (full length)

SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant >95% pure using SDS-PAGE analysis. SDS, WB, in vitro, in vivo Active

SDS-PAGE of ~14 kDa Active Human Recombinant Alpha Synuclein Protein Aggregate .

Toxicity results comparing Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 2) (Catalog No.

Primary rat hippocampal neurons show lewy body inclusion formation when treated with active Alpha Synuclein Protein Aggregate at 4 µg/ml (D-F), but not when treated with control Alpha Synuclein Protein Aggregate at 4 µg/ml (A-C).

Primary rat hippocampal neurons show lewy body inclusion formation when treated with Type 1 Alpha Synuclein Protein Pre-formed Fibrils (ABIN5065829, ABIN5065830 and ABIN5564165) at 4 μg/mL (D-F), but not when treated with Type 2 Alpha Synuclein Protein Pre-formed Fibrils (ABIN5065829, ABIN5065830 and ABIN5564165) at 4 μg/mL (A-C).

ATTO633 fluorescently-labelled alpha synuclein PFFs (ABIN5065829, ABIN5065830 and ABIN5564165) were taken up, transported into the soma, and induced alpha synuclein aggregation in mouse neurocortical primary cells.

Confocal imaging shows NeuN+ (mature) primary cortical neurons filled with ATTO633 fluorescently-labelled alpha synuclein PFFs (ABIN5065829, ABIN5065830 and ABIN5564165).

Immunohistochemistry analysis of rat brain injected with Type 1 human alpha synuclein PFFs (ABIN5065829, ABIN5065830 and ABIN5564165).

TEM of Type 1 Alpha Synuclein Pre-formed Fibrils (PFFs) (ABIN5065829, ABIN5065830 and ABIN5564165)

Type 1 alpha synuclein Pre-formed Fibrils (ABIN5065829, ABIN5065830 and ABIN5564165) seed the formation of new alpha synuclein fibrils from the pool of alpha synuclein monomers (ABIN5065829, ABIN5065830 and ABIN5564165).

TEM of Type 1 Alpha Synuclein Pre-formed Fibrils (PFFs) (ABIN5065829, ABIN5065830 and ABIN5564165)

10 images

Catalog No. ABIN5065829

SNCA Protein (AA 1-140) (His tag)

custom-made SNCA Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant SNCA Protein, UniprotID P37840

AlphaFold protein structure predicition of Human Recombinant SNCA Protein, UniprotID P37840

AlphaFold protein structure predicition of Human Recombinant SNCA Protein, UniprotID P37840

3 images

Catalog No. ABIN7544253

SNCA Protein (AA 1-140) (His tag)

custom-made SNCA Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Snca Protein, UniprotID O55042

AlphaFold protein structure predicition of Mouse Recombinant Snca Protein, UniprotID O55042

AlphaFold protein structure predicition of Mouse Recombinant Snca Protein, UniprotID O55042

3 images

Catalog No. ABIN7562469

SNCA Protein

SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE

Western Blotting (WB) image for Synuclein, alpha (SNCA) protein (ABIN7320688)

1 image

Catalog No. ABIN7320688

SNCA Protein (AA 1-140) (His tag)

SNCA Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

Western Blotting (WB) image for Synuclein, alpha (SNCA) (AA 1-140) protein (His tag) (ABIN7125301)

1 image

Catalog No. ABIN7125301

SNCA Protein (active)

SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure SDS

Figure annotation denotes ug of protein loaded and % gel used.

1 image

Catalog No. ABIN934871

SNCA Protein (AA 31-140) (GST tag)

SNCA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Image no. 1 for Synuclein, alpha (SNCA) (AA 31-140) protein (GST tag) (ABIN1320776)

1 image

Catalog No. ABIN1320776

SNCA Protein (AA 1-140) (GST tag)

SNCA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Image no. 1 for Synuclein, alpha (SNCA) (AA 1-140) protein (GST tag) (ABIN1320774)

1 image

Catalog No. ABIN1320774

SNCA Protein (AA 1-139, partial) (GST tag)

SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % SDS, ELISA

SDS-PAGE (SDS) image for Synuclein, alpha (SNCA) (AA 1-139), (partial) protein (GST tag) (ABIN1046507)

1 image

3 references

Catalog No. ABIN1046507

SNCA Protein (AA 1-140)

SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Catalog No. ABIN7504231

SNCA Protein (AA 1-140) (His tag)

SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.

Catalog No. ABIN7505128

SNCA Protein (AA 1-140) (His tag)

SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.

Catalog No. ABIN7505351

SNCA Protein (His tag)

SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.

Catalog No. ABIN7319207

SNCA Protein (AA 1-140)

SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.

Catalog No. ABIN4371752

SNCA Protein (His tag)

SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA

Catalog No. ABIN7579612

SNCA Protein (AA 23-140) (His tag)

SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, PC, Imm

Catalog No. ABIN7393487

SNCA Protein (AA 23-140) (His tag)

SNCA Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, PC, Imm

Catalog No. ABIN7405657

SNCA Protein (AA 1-140) (Strep Tag)

custom-made SNCA Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

Catalog No. ABIN3131854

show more results

Did you look for something else?

You are here: