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anti-Human CBL antibody for ELISA

Recommended CBL Antibody (supplied by: Log in to see )

Antigen
Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) Antibodies
  • 4732447J05Rik
  • Cbl-2
  • c-Cbl
  • cbl
  • C-CBL
  • CBL2
  • FRA11B
  • NSLL
  • RNF55
  • c-cbl-like
  • RGD1561386
  • Casitas B-lineage lymphoma
  • Cbl proto-oncogene, E3 ubiquitin protein ligase
  • Cbl
  • CBL
Reactivity
Human, Mouse (Murine), Rat (Rattus)
254
169
159
7
6
4
4
3
3
1
1
1
Host
Mouse
206
37
16
1
Clonality
Monoclonal
Conjugate
This CBL antibody is un-conjugated
7
7
7
7
6
5
5
5
5
5
5
5
5
5
4
2
2
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
176
70
65
65
56
43
19
14
8
6
5
3
3
3
1
1
1
1
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Catalog No. ABIN968993
$ 430.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.928496 ABIN4288401 ELISA FACS ICC IF IHC WB Mouse IgG1 Log in to see 3B12
11.928496 ABIN560198 IP ELISA WB Mouse IgG1 kappa AA 736-835, partial Log in to see 6D12
11.928496 ABIN1845278 ELISA FACS IF/ICC IHC WB Mouse IgG1 Log in to see
1 ABIN1531307 IF IHC ELISA WB Rabbit IgG pTyr700 Log in to see Polyclonal 1
1 ABIN1531308 IHC ELISA WB Rabbit IgG pTyr674 Log in to see Polyclonal
1 ABIN1531306 IF IHC ELISA WB Rabbit IgG pTyr774 Log in to see Polyclonal
1 ABIN1532325 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1532326 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1532327 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN3183701 ELISA IF IHC WB Rabbit IgG Ser207 Log in to see Polyclonal
1 ABIN3183702 ELISA IF IHC WB Rabbit IgG Ser208 Log in to see Polyclonal
1 ABIN3183703 ELISA IHC WB Rabbit IgG Ser209 Log in to see Polyclonal
1 ABIN292894 ELISA WB Goat AA 893-906 Log in to see Polyclonal
1 ABIN342872 ELISA WB Rabbit pTyr700 Log in to see Polyclonal
1 ABIN2888650 IF IHC (p) ELISA WB Rabbit IgG AA 740-789 Log in to see Polyclonal
1 ABIN2888651 IF IHC (p) ELISA WB Rabbit IgG AA 666-715 Log in to see Polyclonal
1 ABIN2888652 IHC (p) ELISA WB Rabbit IgG AA 640-689 Log in to see Polyclonal
1 ABIN1001990 FM ELISA WB Rabbit IgG Log in to see Polyclonal 3
1 ABIN514073 ELISA WB Mouse IgG1 kappa AA 736-835, partial Log in to see 6D12
1 ABIN514072 ELISA WB Mouse IgG1 kappa AA 736-835, partial Log in to see 6D12

Top referenced anti-CBL antibody for ELISA

Similar anti-CBL Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 42 Antibodies 47 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 3 Antibodies
Flow Cytometry (FACS) 7 Antibodies 7 Antibodies
Fluorescence Microscopy (FM) 1 Antibodies 1 Antibodies
Immunochromatography (IC) 2 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 9 Antibodies 9 Antibodies
Immunofluorescence (IF) 36 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 4 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 65 Antibodies
Immunohistochemistry (IHC) 45 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 36 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Western Blotting (WB) 97 Antibodies

General

Antigen Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(254), (169), (159), (7), (6), (4), (4), (3), (3), (1), (1), (1)
Host Mouse
(206), (37), (16), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CBL antibody is un-conjugated
(7), (7), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (2), (2)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(176), (70), (65), (65), (56), (43), (19), (14), (8), (6), (5), (3), (3), (3), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-CBL Antibody

Target Details CBL Application Details Handling References for anti-CBL Antibody (ABIN968993) Images
Purification Ascites
Immunogen Purified recombinant fragment of human C-CBL expressed in E. coli.
Clone 3B12
Isotype IgG1

Target Details CBL

Product Details anti-CBL Antibody Application Details Handling References for anti-CBL Antibody (ABIN968993) Images back to top
Antigen
Alternative Name C-CBL (CBL Antibody Abstract)
Background The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.
Molecular Weight 120 kDa
Gene ID 867
HGNC 867
Pathways TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway

Application Details

Product Details anti-CBL Antibody Target Details CBL Handling References for anti-CBL Antibody (ABIN968993) Images back to top
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only

Handling

Product Details anti-CBL Antibody Target Details CBL Application Details References for anti-CBL Antibody (ABIN968993) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.

References for anti-CBL Antibody (ABIN968993)

Product Details anti-CBL Antibody Target Details CBL Application Details Handling Images back to top
Product cited in:

Sproul, Xu, Wilhelm, Gire, Greene: "Cbl negatively regulates JNK activation and cell death." in: Cell research, Vol. 19, Issue 8, pp. 950-61, 2009

Sanada, Suzuki, Shih, Otsu, Kato, Yamazaki, Tamura, Honda, Sakata-Yanagimoto, Kumano, Oda, Yamagata, Takita, Gotoh, Nakazaki, Kawamata, Onodera, Nobuyoshi, Hayashi, Harada, Kurokawa, Chiba, Mori et al.: "Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms. ..." in: Nature, Vol. 460, Issue 7257, pp. 904-8, 2009

Loh, Sakai, Flotho, Kang, Fliegauf, Archambeault, Mullighan, Chen, Bergstraesser, Bueso-Ramos, Emanuel, Hasle, Issa, van den Heuvel-Eibrink, Locatelli, Stary, Trebo, Wlodarski, Zecca, Shannon et al.: "Mutations in CBL occur frequently in juvenile myelomonocytic leukemia. ..." in: Blood, Vol. 114, Issue 9, pp. 1859-63, 2009

Images

Product Details anti-CBL Antibody Target Details CBL Application Details Handling References for anti-CBL Antibody (ABIN968993) back to top
Supplier Images
ELISA image for anti-CBL antibody (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence) (ABIN968993) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-CBL antibody (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence) (ABIN968993) Figure 2: Flow cytometric analysis of MCF-7 cells using C-CBL mouse mAb (blue) and ne...
Immunocytochemistry (ICC) image for anti-CBL antibody (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence) (ABIN968993) Figure 3: Immunofluorescence analysis of Hela cells using C-CBL mouse mAb (green) . B...
Immunohistochemistry (IHC) image for anti-CBL antibody (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence) (ABIN968993) Figure 4: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues us...
Immunohistochemistry (IHC) image for anti-CBL antibody (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence) (ABIN968993) Figure 5: Immunohistochemical analysis of paraffin-embedded bladder cancer tissues us...
Western Blotting (WB) image for anti-CBL antibody (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence) (ABIN968993) Figure 6: Western blot analysis using C-CBL mouse mAb against RAJI (1), RAW264.7 (2),...
Western Blotting (WB) image for anti-CBL antibody (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence) (ABIN968993) Figure 7: Western blot analysis using C-CBL mAb against human C-CBL (AA: 684-865) rec...