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TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 ELISA Kits (TAB2)
On www.antibodies-online.com are 7 TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) ELISA Kits from 5 different suppliers available. Additionally we are shipping TAB2 Antibodies (62) and TAB2 Proteins (2) and many more products for this protein. A total of 78 TAB2 products are currently listed.
Synonyms:
1110030N06Rik, A530078N03Rik, CHTD2, map3k7ip2, mKIAA0733, zgc:77446

TAB2 (TAB2) ELISA Kits by Reactivity

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Human TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) interaction partners

  1. Data suggest that mRNA/protein levels of NLRP6 (show NLRP6 ELISA Kits) are down-regulated in synovial tissues and synoviocytes of rheumatoid arthritis (RA) patients compared to osteoarthritis patients; NLRP6 (show NLRP6 ELISA Kits) provides docking site to facilitate interaction between TAB2/3 and TRIM38 (show TRIM38 ELISA Kits) in RA synoviocytes in response to TNFalpha (show TNF ELISA Kits). (NLRP6 (show NLRP6 ELISA Kits) = ; TAB2/3 = transforming growth factor-b (show ATP5S ELISA Kits)-activated kinase 1-binding protein 2/3; TRIM38 (show TRIM38 ELISA Kits) = tripartite motif 38)

  2. A Novel Functional Domain of Tab2 Involved in the Interaction with Estrogen Receptor Alpha (show ESR1 ELISA Kits) in Breast Cancer Cells

  3. The expression of miR (show MLXIP ELISA Kits)-155 target gene, TAB2, and the downstream gene, iNOS (show NOS2 ELISA Kits), were found to be inhibited in psoriatic dermal mesenchymal stem cells.

  4. DK1 (show DOLK ELISA Kits) inhibits the formation of the TAK1 (show MAP3K7 ELISA Kits)-TAB2-TRAF6 (show TRAF6 ELISA Kits) complex and leads to the inhibition of TRAF6 (show TRAF6 ELISA Kits) ubiquitination.

  5. Authors demonstrate that enterovirus 71 3C interacts with TAB2 and TAK1 (show MAP3K7 ELISA Kits) and suppresses cytokine expression via cleavage of the TAK1 (show MAP3K7 ELISA Kits) complex proteins.

  6. SUMOylation may serve as a novel mechanism for the regulation of TAB2.

  7. conclude that TRIM38 (show TRIM38 ELISA Kits) negatively regulates TNFalpha (show TNF ELISA Kits)- and IL-1beta (show IL1B ELISA Kits)-induced signaling by mediating lysosome-dependent degradation of TAB2/3, two critical components in TNFalpha (show TNF ELISA Kits)- and IL-1beta (show IL1B ELISA Kits)-induced signaling pathways

  8. These data indicate that overexpression of TRIM22 (show TRIM22 ELISA Kits) may negatively regulate the TRAF6 (show TRAF6 ELISA Kits)-stimulated NF-kappaB (show NFKB1 ELISA Kits) pathway by interacting with and degrading TAB2.

  9. our data implicate Tab2 as a mediator of resistance to endocrine therapy and as a potential new target to reverse pharmacological resistance and potentiate antiestrogen action.

  10. We found that endothelial TAK1 (show MAP3K7 ELISA Kits) and TAB2, but not TAB1 (show TAB1 ELISA Kits), were critically involved in vascular formation

Mouse (Murine) TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) interaction partners

  1. These findings support a regulatory role for TGF-beta-activated kinase 1 (show MAP3K7 ELISA Kits) in governing downstream MAPKs/NF-kappaB (show NFKB1 ELISA Kits) signaling cascades in the macrophage activation in response to hyperglycemic insult

  2. RNF4 (show RNF4 ELISA Kits) negatively regulates NF-kappaB (show NFKB1 ELISA Kits) signaling by down-regulating TAB2

  3. TAB1 (show TAB1 ELISA Kits) and TAB2 are required for activated macrophages, making TAB1 (show TAB1 ELISA Kits) and TAB2 effective targets to control inflammation by modulating macrophage survival.

  4. Loss of Tab2 is associated with liver injury.

  5. miR (show MLXIP ELISA Kits)-155 inhibits the immunosuppressive capacity of MSCs by reducing iNOS (show NOS2 ELISA Kits) expression by targeting TAB2.

  6. TAB2 and TAB3 (show TAB3 ELISA Kits) are essential for B cell activation (show BLNK ELISA Kits) leading to antigen-specific antibody responses, as well as B-1 and marginal zone B cell development.

  7. We found that endothelial TAK1 (show NR2C2 ELISA Kits) and TAB2, but not TAB1 (show TAB1 ELISA Kits), were critically involved in vascular formation

  8. MiR (show MLXIP ELISA Kits)-23b suppresses IL-17 (show IL17A ELISA Kits)-, tumor necrosis factor alpha (TNF-alpha (show TNF ELISA Kits))- or IL-1beta (show IL1B ELISA Kits)-induced NF-kappaB (show NFKB1 ELISA Kits) activation and inflammatory cytokine expression by targeting TAB2, TAB3 (show TAB3 ELISA Kits) and IKK-alpha (show CHUK ELISA Kits).

  9. Epithelial TAK1 (show NR2C2 ELISA Kits) activity is regulated through two unique, TAB1 (show TAB1 ELISA Kits)-dependent basal & TAB2-mediated stimuli-dependent mechanisms.

  10. TAK1 (show NR2C2 ELISA Kits) and its adapter protein (show GRB10 ELISA Kits), TAB2, reciprocally regulate both TAK1 (show NR2C2 ELISA Kits)- and ASK1 (show MAP3K5 ELISA Kits)-mediated signaling pathways to direct the activations of NF-kappaB (show NFKB1 ELISA Kits) and AP-1 (show JUN ELISA Kits).

Zebrafish TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) interaction partners

  1. a critical, dosage-sensitive role during development was demonstrated by the cardiac defects observed upon titrated knockdown of tab2 expression in zebrafish embryos

TAB2 Antigen Profile

Antigen Summary

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.

Alternative names and synonyms associated with TAB2

  • TGF-beta activated kinase 1/MAP3K7 binding protein 2 (TAB2) Elisa Kit
  • TGF-beta activated kinase 1/MAP3K7 binding protein 2 (Tab2) Elisa Kit
  • TGF-beta activated kinase 1/MAP3K7 binding protein 2 (tab2) Elisa Kit
  • 1110030N06Rik Elisa Kit
  • A530078N03Rik Elisa Kit
  • CHTD2 Elisa Kit
  • map3k7ip2 Elisa Kit
  • mKIAA0733 Elisa Kit
  • zgc:77446 Elisa Kit

Protein level used designations for TAB2

TGF-beta activated kinase 1/MAP3K7 binding protein 2 , mitogen-activated protein kinase kinase kinase 7-interacting protein 2-like , TAB-2 , TAK1-binding protein 2 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 , TGF-beta-activated kinase 1-binding protein 2 , mitogen-activated protein kinase kinase kinase 7-interacting protein 2 , mitogen-activated protein kinase kinase kinase 7 interacting protein 2 , Tak1 binding protein 2 , mitogen activated protein kinase kinase kinase 7 interacting protein 2 , mitogen-activated protein kinase kinase kinase 7-interacting protein 2 homolog

GENE ID SPECIES
100026855 Monodelphis domestica
100414129 Callithrix jacchus
100597932 Nomascus leucogenys
23118 Homo sapiens
421622 Gallus gallus
484028 Canis lupus familiaris
540203 Bos taurus
68652 Mus musculus
308267 Rattus norvegicus
494163 Danio rerio
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