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TMEM189 is a target gene of the BACH1 (show BACH1 Proteins) transcription factor according to ChIP-seq analysis in HEK (show EPHA3 Proteins) 293 cells.
Co-transcription of this gene and the neighboring downstream gene (ubiquitin-conjugating enzyme E2 variant 1) generates a rare read-through transcript, which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. The protein encoded by this individual gene lacks a UEV1 domain but includes three transmembrane regions. Alternative splicing results in multiple transcript variants.
ubiquitin-conjugating enzyme E2 variant 1
, Ubiquitin-conjugating enzyme E2 variant 1
, transmembrane protein 189
, Kua homolog
, TMEM189-UBE2V1 readthrough transcript
, Transmembrane protein 189
, ubiquitin-conjugating enzyme variant Kua