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Browse our anti-TAB2 (TAB2) Antibodies

Full name:
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 Antibodies (TAB2)
On www.antibodies-online.com are 49 TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) Antibodies from 16 different suppliers available. Additionally we are shipping TAB2 Kits (4) and TAB2 Proteins (2) and many more products for this protein. A total of 61 TAB2 products are currently listed.
Synonyms:
1110030N06Rik, A530078N03Rik, CHTD2, map3k7ip2, mKIAA0733, zgc:77446

Most Popular Reactivities for anti-TAB2 (TAB2) Antibodies

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anti-Human TAB2 Antibodies:

anti-Mouse (Murine) TAB2 Antibodies:

anti-Rat (Rattus) TAB2 Antibodies:

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Top referenced anti-TAB2 Antibodies

  1. Human Polyclonal TAB2 Primary Antibody for EIA, IHC (p) - ABIN1449964 : Mizukami, Takaesu, Akatsuka, Sakurai, Ninomiya-Tsuji, Matsumoto, Sakurai: Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6. in Molecular and cellular biology 2002 (PubMed)
    Show all 3 references for ABIN1449964

  2. Human Monoclonal TAB2 Primary Antibody for FACS, ELISA - ABIN969430 : Häcker, Karin: Regulation and function of IKK and IKK-related kinases. in Science's STKE : signal transduction knowledge environment 2006 (PubMed)
    Show all 3 references for ABIN969430

  3. Chicken Polyclonal TAB2 Primary Antibody for IHC, WB - ABIN2779619 : Kanayama, Seth, Sun, Ea, Hong, Shaito, Chiu, Deng, Chen: TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains. in Molecular cell 2004 (PubMed)
    Show all 2 references for ABIN2779619

  4. Human Monoclonal TAB2 Primary Antibody for EIA, FACS - ABIN1109193 : Simmonds, Heward, Carr-Smith, Foxall, Franklyn, Gough: Contribution of single nucleotide polymorphisms within FCRL3 and MAP3K7IP2 to the pathogenesis of Graves' disease. in The Journal of clinical endocrinology and metabolism 2006 (PubMed)

More Antibodies against TAB2 Interaction Partners

Human TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) interaction partners

  1. DK1 (show DOLK Antibodies) inhibits the formation of the TAK1 (show MAP3K7 Antibodies)-TAB2-TRAF6 (show TRAF6 Antibodies) complex and leads to the inhibition of TRAF6 (show TRAF6 Antibodies) ubiquitination.

  2. Authors demonstrate that enterovirus 71 3C interacts with TAB2 and TAK1 (show MAP3K7 Antibodies) and suppresses cytokine expression via cleavage of the TAK1 (show MAP3K7 Antibodies) complex proteins.

  3. SUMOylation may serve as a novel mechanism for the regulation of TAB2.

  4. conclude that TRIM38 (show TRIM38 Antibodies) negatively regulates TNFalpha (show TNF Antibodies)- and IL-1beta (show IL1B Antibodies)-induced signaling by mediating lysosome-dependent degradation of TAB2/3, two critical components in TNFalpha (show TNF Antibodies)- and IL-1beta (show IL1B Antibodies)-induced signaling pathways

  5. These data indicate that overexpression of TRIM22 (show TRIM22 Antibodies) may negatively regulate the TRAF6 (show TRAF6 Antibodies)-stimulated NF-kappaB (show NFKB1 Antibodies) pathway by interacting with and degrading TAB2.

  6. our data implicate Tab2 as a mediator of resistance to endocrine therapy and as a potential new target to reverse pharmacological resistance and potentiate antiestrogen action.

  7. We found that endothelial TAK1 (show MAP3K7 Antibodies) and TAB2, but not TAB1 (show TAB1 Antibodies), were critically involved in vascular formation

  8. MiR (show MLXIP Antibodies)-23b suppresses IL-17 (show IL17A Antibodies)-, tumor necrosis factor alpha (TNF-alpha (show TNF Antibodies))- or IL-1beta (show IL1B Antibodies)-induced NF-kappaB (show NFKB1 Antibodies) activation and inflammatory cytokine expression by targeting TAB2, TAB3 (show TAB3 Antibodies) and IKK-alpha (show CHUK Antibodies).

  9. TAK1 (show MAP3K7 Antibodies) and its adapter protein (show TOLLIP Antibodies), TAB2, reciprocally regulate both TAK1 (show MAP3K7 Antibodies)- and ASK1 (show MAP3K5 Antibodies)-mediated signaling pathways to direct the activations of NF-kappaB (show NFKB1 Antibodies) and AP-1 (show FOSB Antibodies).

  10. human TAB2 and TAB3 (show TAB3 Antibodies), ubiquitin-chain sensory proteins involved in NF-kappaB (show NFKB1 Antibodies) signalling, are directly inactivated by enteropathogenic Escherichia coli NleE, a conserved bacterial type-III-secreted effector responsible for blocking host NF-kappaB (show NFKB1 Antibodies) signalling

Mouse (Murine) TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) interaction partners

  1. RNF4 (show RNF4 Antibodies) negatively regulates NF-kappaB (show NFKB1 Antibodies) signaling by down-regulating TAB2

  2. TAB1 (show TAB1 Antibodies) and TAB2 are required for activated macrophages, making TAB1 (show TAB1 Antibodies) and TAB2 effective targets to control inflammation by modulating macrophage survival.

  3. Loss of Tab2 is associated with liver injury.

  4. miR (show MLXIP Antibodies)-155 inhibits the immunosuppressive capacity of MSCs by reducing iNOS (show NOS2 Antibodies) expression by targeting TAB2.

  5. TAB2 and TAB3 (show TAB3 Antibodies) are essential for B cell activation (show BLNK Antibodies) leading to antigen-specific antibody responses, as well as B-1 and marginal zone B cell development.

  6. We found that endothelial TAK1 (show NR2C2 Antibodies) and TAB2, but not TAB1 (show TAB1 Antibodies), were critically involved in vascular formation

  7. MiR (show MLXIP Antibodies)-23b suppresses IL-17 (show IL17A Antibodies)-, tumor necrosis factor alpha (TNF-alpha (show TNF Antibodies))- or IL-1beta (show IL1B Antibodies)-induced NF-kappaB (show NFKB1 Antibodies) activation and inflammatory cytokine expression by targeting TAB2, TAB3 (show TAB3 Antibodies) and IKK-alpha (show CHUK Antibodies).

  8. Epithelial TAK1 (show NR2C2 Antibodies) activity is regulated through two unique, TAB1 (show TAB1 Antibodies)-dependent basal & TAB2-mediated stimuli-dependent mechanisms.

  9. TAK1 (show NR2C2 Antibodies) and its adapter protein (show GRB10 Antibodies), TAB2, reciprocally regulate both TAK1 (show NR2C2 Antibodies)- and ASK1 (show MAP3K5 Antibodies)-mediated signaling pathways to direct the activations of NF-kappaB (show NFKB1 Antibodies) and AP-1 (show JUN Antibodies).

  10. Wnt3a (show WNT3A Antibodies) stimulation led to an increase in the interaction of TAB2 with NLK (show NLK Antibodies) and the formation of a TAK1 (show NR2C2 Antibodies).TAB2.NLK (show NLK Antibodies) complex, suggesting that this TAK1 (show NR2C2 Antibodies)-TAB2-NLK (show NLK Antibodies) pathway may constitute a negative feedback mechanism for canonical Wnt (show WNT2 Antibodies) signaling.

Zebrafish TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) interaction partners

  1. a critical, dosage-sensitive role during development was demonstrated by the cardiac defects observed upon titrated knockdown of tab2 expression in zebrafish embryos

TAB2 Antigen Profile

Antigen Summary

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.

Alternative names and synonyms associated with TAB2

  • TGF-beta activated kinase 1/MAP3K7 binding protein 2 (TAB2) antibody
  • TGF-beta activated kinase 1/MAP3K7 binding protein 2 (Tab2) antibody
  • TGF-beta activated kinase 1/MAP3K7 binding protein 2 (tab2) antibody
  • 1110030N06Rik antibody
  • A530078N03Rik antibody
  • CHTD2 antibody
  • map3k7ip2 antibody
  • mKIAA0733 antibody
  • zgc:77446 antibody

Protein level used designations for TAB2

TGF-beta activated kinase 1/MAP3K7 binding protein 2 , mitogen-activated protein kinase kinase kinase 7-interacting protein 2-like , TAB-2 , TAK1-binding protein 2 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 , TGF-beta-activated kinase 1-binding protein 2 , mitogen-activated protein kinase kinase kinase 7-interacting protein 2 , mitogen-activated protein kinase kinase kinase 7 interacting protein 2 , Tak1 binding protein 2 , mitogen activated protein kinase kinase kinase 7 interacting protein 2 , mitogen-activated protein kinase kinase kinase 7-interacting protein 2 homolog

GENE ID SPECIES
100026855 Monodelphis domestica
100414129 Callithrix jacchus
100597932 Nomascus leucogenys
23118 Homo sapiens
421622 Gallus gallus
484028 Canis lupus familiaris
540203 Bos taurus
68652 Mus musculus
308267 Rattus norvegicus
494163 Danio rerio
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