Browse our Lactoferrin Proteins (LTF)

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Lactotransferrin Proteins (LTF)
On are 43 Lactotransferrin (LTF) Proteins from 11 different suppliers available. Additionally we are shipping Lactoferrin Antibodies (478) and Lactoferrin Kits (87) and many more products for this protein. A total of 615 Lactoferrin products are currently listed.
conalbumin, Csp82, GIG12, HLF2, Lf, LTF, MMS10R, Ms10r, PLF, TFEW
list all proteins Gene Name GeneID UniProt
LTF 4057 P02788
LTF 17002 P08071
LTF 301034  

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Lactoferrin Proteins (LTF) by Origin

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Top referenced Lactoferrin Proteins

  1. Human Lactoferrin Protein expressed in Human Cells - ABIN2003977 : Azzam, Goertz, Fritts, Jonas: Natural products and chronic hepatitis C virus. in Liver international : official journal of the International Association for the Study of the Liver 2007 (PubMed)

More Proteins for Lactoferrin Interaction Partners

Human Lactotransferrin (LTF) interaction partners

  1. Lactoferrin is a nonheme iron-binding glycoprotein strongly expressed in human and bovine milk and it plays many functions during infancy such as iron homeostasis and defense against microorganisms. [Review]

  2. Faecal biomarkers lactoferrin, calprotectin (show S100A8 Proteins), and PMN-elastase (show ELANE Proteins) were able to distinguish between ulcerative colitis patients with mucosal healing from clinical remission and mild disease, showed significant correlations with endoscopy, and were predictive of a flare.

  3. Review of the many ways lactoferrin influences the complex immune machinery and the known and putative mechanisms that may explain its properties.

  4. Review of the role of lactoferrin in gastrointestinal and immune development and function. Preclinical findings support clinical studies demonstrating benefits of dietary lactoferrin in the prevention of infections, late onset sepsis, and necrotizing enterocolitis.

  5. This review discusses the current state of knowledge of lactoferrin as a conditional nutrient for neurodevelopment, neuroprotection, and cognitive function during the period of rapid brain growth.

  6. Review of the role of lactoferrin in infant gut (show GUSB Proteins) health and gut (show GUSB Proteins) immune development and functions, including the lactoferrin effects on the neonatal microbiome, and its role in preventing infections in infants and toddlers.

  7. Very large differences in Lactoferrin (LF) concentrations between meconium portions and in the total LF accumulation between the neonates suggest the influence of intrauterine factors on the variations in fetal intestinal LF concentrations.

  8. Because microbes actively target lactoferrin to acquire iron, we propose that the emergence of antimicrobial activity provided a pivotal mechanism of adaptation sparking evolutionary conflicts via acquisition of new protein functions.

  9. Most of the variation in the ability of human apo (show C9orf3 Proteins)-hLf (show EPAS1 Proteins) to kill Streptococcus pneumoniae is dependent on the variation in the binding of apo (show C9orf3 Proteins)-hLf (show EPAS1 Proteins) to surface PspA and this binding is dependent on variation in PspA as well as variation in capsule which may enhance killing by reducing the binding of apo (show C9orf3 Proteins)-hLf (show EPAS1 Proteins) to PspA.

  10. These observations suggest that lactoferrin serves as an intrinsic inhibitor of NETs release into the circulation. Thus, lactoferrin may represent a therapeutic lead for controlling NETs release in autoimmune and/or inflammatory diseases.

Cow (Bovine) Lactotransferrin (LTF) interaction partners

  1. Retinoic acid enhanced TbetaRIII expression and that this increase contributed to LF-stimulated IgA production.

  2. lactoferrin and glutamate receptor-interacting protein 1 (show GRIP1 Proteins) showed a twofold increase during the controlled internal drug release -induced estrous stage compared to the levels in non-estrous stage in bovine cervical mucus

  3. Review of preclinical studies in piglets fed bovine lactoferrin demonstrating the role of lactoferrin in gastrointestinal and immune development and function.

  4. Review of preclinical studies in piglets fed bovine lactoferrin demonstrating the role of lactoferrin in neurodevelopment and cognition.

  5. Bovine lactoferrin SNPs -270T>C and -156A>G showed close linkage disequilibrium (r(2)=0.76). The SNP -190G>A showed a significant association with SCS (show TWIST1 Proteins), and individuals with genotype GG had higher SCS (show TWIST1 Proteins) than genotypes AG and AA.

  6. Lf upregulated several canonical signaling pathways associated with neurodevelopment and cognition and influenced ~10 genes involved in the brain-derived neurotrophin (show BDNF Proteins) factor (BDNF (show BDNF Proteins)) signaling pathway.

  7. Results from this study indicated the probable role played by Lactoferrin promoter to serve as candidate gene for mastitis susceptibility among indigenous and crossbred milch cattle.

  8. Supplementation with lactoferrin (1,600 mg/kg per day) effectively suppressed the increase in transepidermal water loss, reduction in skin hydration, aberrant epidermal hyperplasia, and cell apoptosis induced by UV irradiation.

  9. Bovine Lf can capture and terminate the cycle of ROS (show ROS1 Proteins) production by heme iron. Luminal iron binding properties of Lf might assist in regulating excess levels of stored iron and down-regulate ferritin (show FTL Proteins) production and associated pro-inflammatory signaling.

  10. The results showed potent stimulation of the proliferative response of PBMC by bovine lactoferrin, associated with the induction of proinflammatory cytokines only in the case of colostral bovine lactoferrin.

Mouse (Murine) Lactotransferrin (LTF) interaction partners

  1. Data indicate that lactoferrin uptake across duodenum by glyceraldehyde-3-phosphate dehydrogenase (GAPDH (show GAPDH Proteins)).

  2. Results show that LTF gene expression is downregulated in colorectal cancer tumors and its knock out in mouse model of colitis-associated colorectal dysplasia suggests its protective role in colorectal mucosal immunity and inflammation.

  3. Data show that the expression of several genes encoding salivary antimicrobial proteins, such as secretory leukocyte peptidase inhibitor (SLPI (show SLPI Proteins)), S100A8 (show S100A8 Proteins), and lactotransferrin, was reduced due to myeloid differentiation dactor 88 (MyD88 (show MYD88 Proteins)) deficiency.

  4. Lactoferrin dampens high-fructose corn syrup-induced hepatic manifestations of the metabolic syndrome in a murine model.

  5. We conclude that lactotransferrin represents a late stage differentiation marker of neutrophils, macrophages and distinct subtypes of dendritic cells.

  6. The variations in lactoferrin expression levels during developmental stages may be related to its regulatory role in mouse mammary gland immunity.

  7. the present work indicated that LF stimulated MC3T3-E1 preosteoblast differentiation mainly through LRP1 (show LRP1 Proteins)-independent PKA and p38 (show CRK Proteins) signaling pathways.

  8. Studie indicate that in iCre knock-in line, the iCre is expressed from endogenous lactoferrin (Ltf) promoter.

  9. administration of lactoferrin led to autopotentiated increased expression of the LTF gene. The decreased lactoferrin mRNA levels in association with obesity and diabetes were replicated in mice adipose tissue

  10. The up-regulation of lactorferrin in the brains of the transgenic mouse model of Alzheimer's disease provides evidence of an important role for lactoferrin in alzheimer disease-affected brain tissues

Horse (Equine) Lactotransferrin (LTF) interaction partners

  1. lactoferrin was found in the cytoplasm of principal cells in the corpus and cauda of the epididymis in peri (show PLIN1 Proteins)- and post-pubertal, but not pre-pubertal stallions. Further, lactoferrin binds to sperm, suggesting a role for protection or regulation of sperm.

  2. These data indicate that clinically normal skin of horses affected by CHS is not characterized by modified maintenance levels of lactoferrin mRNA.

Pig (Porcine) Lactotransferrin (LTF) interaction partners

  1. this paper shows that recombinant lactoferrin peptide LF-6 produced with intein technology has both antibacterial and immunomodulatory activity in mice

  2. We propose that lactoferrin functions in the immune defense of the small intestinal mucosa by targeting the population of T cells in the lamina propria

  3. Involvement of HSP27 (show HSPB1 Proteins) and lactoferrin in porcine endometrium and neutrophils activity.

  4. Growth performance of animal pups is enhanced by directly feeding the genetically engineered milk containing enriched pLF protein in transgenic mice.

Lactoferrin (LTF) Protein Profile

Protein Summary

This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Lactoferrin (LTF)

  • lactotransferrin (LTF)
  • lactotransferrin (CpipJ_CPIJ000114)
  • lactotransferrin (LOC100231086)
  • lactoferrin (LOC554321)
  • lactoferrin-like (LOC100348741)
  • lactotransferrin (Ltf)
  • transferrin (ovotransferrin) (TF)
  • conalbumin protein
  • Csp82 protein
  • GIG12 protein
  • HLF2 protein
  • Lf protein
  • LTF protein
  • MMS10R protein
  • Ms10r protein
  • PLF protein
  • TFEW protein

Protein level used designations for Lactotransferrin Proteins (LTF)

lactotransferrin , lactotransferrin-like , growth-inhibiting protein 12 , neutrophil lactoferrin , talalactoferrin , lactoferrin , N lobe , minisatellite 10r detected by probe MMS10 , allergen Gal d III , ovotransferrin , ovotransferrin BB type , ovotransferrin BC type , ovotransferrin CC type , serum transferrin

460325 Pan troglodytes
6030911 Culex quinquefasciatus
100015908 Monodelphis domestica
100231086 Taeniopygia guttata
100399865 Callithrix jacchus
100438577 Pongo abelii
100581103 Nomascus leucogenys
554321 Ovis aries
100348741 Oryctolagus cuniculus
4057 Homo sapiens
280846 Bos taurus
484787 Canis lupus familiaris
17002 Mus musculus
100861194 Capra hircus
100033944 Equus caballus
397649 Sus scrofa
301034 Rattus norvegicus
396241 Gallus gallus
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