Browse our Prion Protein 2 (Dublet) Proteins (PRND)

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Prion Protein 2 (Dublet) Proteins (PRND)
On are 11 Prion Protein 2 (Dublet) (PRND) Proteins from 6 different suppliers available. Additionally we are shipping Prion Protein 2 (Dublet) Antibodies (24) and Prion Protein 2 (Dublet) Kits (9) and many more products for this protein. A total of 46 Prion Protein 2 (Dublet) products are currently listed.
AI450264, dJ1068H6.4, doppel, Dpl, PRND, PrPLP
list all proteins Gene Name GeneID UniProt
PRND 23627 Q9UKY0
Rat PRND PRND 113910  
PRND 26434 Q9QUG3

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Prion Protein 2 (Dublet) Proteins (PRND) by Origin

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Top referenced Prion Protein 2 (Dublet) Proteins

  1. Human PRND Protein expressed in Escherichia coli (E. coli) - ABIN1098521 : Peoch, Guérin, Brandel, Launay, Laplanche: First report of polymorphisms in the prion-like protein gene (PRND): implications for human prion diseases. in Neuroscience letters 2000 (PubMed)
    Show all 2 references for 1098521

More Proteins for Prion Protein 2 (Dublet) Interaction Partners

Human Prion Protein 2 (Dublet) (PRND) interaction partners

  1. results demonstrate that blocking doppel can control VEGF signaling in TECs and selectively inhibit tumor angiogenesis.

  2. The association between the APOE (show APOE Proteins), CYP46 (show CYP46A1 Proteins), PRNP (show PRNP Proteins) and PRND genes and the profile of neuropsychiatric symptoms in Polish subjects with Alzheimer's disease and mild cognitive impairment, was evaluated.

  3. in astrocytomas, Dpl undergoes different molecular processes that might constitute additional helpful tools to characterize the glial tumor progression

  4. Cytotoxicity induced by the expression of Dpl and truncated PrP (show C4BPA Proteins) in neural derived cells are closely related with the apoptosis process.

  5. expression pattern and biochemical characteristics in human tissues and in Chinese hamster ovary cells transfected with wild-type or variant human Dpl gene constructs

  6. Doppel expression is not modified in the brains of patients with Creutzfeldt-Jakob disease.

  7. human Doppel fails to interact with itself; Dpl and PrP (show C4BPA Proteins) are not related or are only marginally related with respect to their ligand binding behaviour

  8. results demonstrate that Doppel and PrPc (show PRNP Proteins) co-patch extensively at the plasma membrane

  9. Doppel interacts with the full-length laminin receptor precursor protein

  10. Doppel is expressed early during ontogenesis, and is found in both germ cells and Sertoli cells. Doppel may play a physiological role in acrosome biogenesis.

Cow (Bovine) Prion Protein 2 (Dublet) (PRND) interaction partners

  1. Disparate Modes of Evolution Shaped Modern Prion (PRNP (show PRNP Proteins)) and Prion (show PRNP Proteins)-Related Doppel (PRND) Variation in Domestic Cattle

  2. Results showed that the region -323/+32 (+1 is the transcription start site) represents the promoter region and contains positive cis (show CISH Proteins)-acting elements

  3. the genomic structure of three genes, PRNP (show PRNP Proteins), PRND, and RASSF2 (show RASSF2 Proteins), within the syntenic region of the bovine genome is highly conserved in order and orientation.

Mouse (Murine) Prion Protein 2 (Dublet) (PRND) interaction partners

  1. in GC-1 spg cells, phosphorylation of p21 and N-terminal truncated PrP may play roles in the control of Dpl-induced apoptosis, which may benefit the physiological function of Dpl in the male reproduction system.

  2. Data suggest that glycosylation status of the prion protein (show PRNP Proteins) and yet-to-be-identified proteases modulate internal C1 and C2 endoproteolysis of Doppel (doppelganger prion (show PRNP Proteins)) and Shadoo (shadow of prion protein (show SPRN Proteins)) in mouse neurons.

  3. Data on residue secondary structure propensities suggest that novel beta-sheets of doppel protein (Prnd) and prion protein (Prnp (show PRNP Proteins)) are formed by amino acids belonging to helices that are the least stable in the respective native structures.

  4. This finding identifies a protein domain that plays a role in mediating Dpl-related toxicity.

  5. Findings raise the possibility that Bax (show BAX Proteins) and caspase-3 (show CASP3 Proteins) feature in Dpl-mediated apoptosis.

  6. These results indicated that Dpl was glycosylated in a cell type- and tissue-specific manner regardless of PrP(C (show PRNP Proteins)), while PrP(C (show PRNP Proteins)) endoproteolysis was modulated by Dpl expression.

  7. ectopic expression of PrP-like protein Doppel in central neurons induces significant Purkinje cell death resulting in late-onset ataxia (show USP14 Proteins)

  8. We suggest a mechanism for Doppel-mediated Purkinje cell degeneration (show AGTPBP1 Proteins) linked to reduced gene expression of proteins related to neuronal activity.

  9. interaction between Dpl and PrPC (show PRNP Proteins) occurs in lipid rafts and is dependent on the integrity of these membrane microdomains

  10. Expression of doppel in the CNS of mice does not modulate transmissible spongiform encephalopathy disease

Prion Protein 2 (Dublet) (PRND) Protein Profile

Protein Summary

This gene is found on chromosome 20, approximately 20 kbp downstream of the gene encoding cellular prion protein, to which it is biochemically and structurally similar. The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that is found predominantly in testis. Mutations in this gene may lead to neurological disorders.

Alternative names and synonyms associated with Prion Protein 2 (Dublet) (PRND)

  • prion protein 2 (dublet) (PRND)
  • prion protein 2 (dublet) (Prnd)
  • prion protein dublet (Prnd)
  • AI450264 protein
  • dJ1068H6.4 protein
  • doppel protein
  • Dpl protein
  • PRND protein
  • PrPLP protein

Protein level used designations for PRND

prion protein 2 (dublet) , prion-like protein doppel , prion gene complex, downstream , prion protein dublet , prion protein-like protein , prPLP , prion protein-like protein, doppel , doppelganger

469871 Pan troglodytes
485782 Canis lupus familiaris
100048937 Equus caballus
23627 Homo sapiens
113910 Rattus norvegicus
281426 Bos taurus
443194 Ovis aries
26434 Mus musculus
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